Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands.
Epilepsy Behav. 2012 Feb;23(2):138-41. doi: 10.1016/j.yebeh.2011.11.013. Epub 2012 Jan 10.
Identifying psychiatric disorders rather than psychiatric symptoms might help to distinguish patients with psychogenic nonepileptic seizures (PNES) from those with epileptic seizures (ES). Patients with PNES (n=35), patients with ES (n=35), and healthy controls (n=37) were compared with respect to the prevalence of psychiatric disorders in this study. We tested the predictive power of having axis I psychiatric disorders, as well as personality disorders, in distinguishing ES from PNES. There was no significant difference between the patient groups in the prevalence of axis I psychiatric disorders. Personality disorders were more prevalent in the PNES group than in the ES group (P<0.05). Having a personality disorder was the only predictor for the PNES group. Having a personality disorder seems to be a more significant predictor for PNES than having an axis I psychiatric disorder. Greater attention should be paid to personality disorders in the differentiation of PNES and ES and the provision of effective treatment.
识别精神障碍而非精神症状可能有助于将心因性非癫痫性发作(PNES)患者与癫痫发作(ES)患者区分开来。本研究比较了 35 例 PNES 患者、35 例 ES 患者和 37 例健康对照者的精神障碍患病率。我们测试了是否存在轴 I 精神障碍以及人格障碍是否能区分 ES 和 PNES 的预测能力。患者组之间轴 I 精神障碍的患病率没有显著差异。人格障碍在 PNES 组比在 ES 组更为普遍(P<0.05)。人格障碍是 PNES 组的唯一预测因素。与轴 I 精神障碍相比,人格障碍似乎是 PNES 的更重要预测因素。在区分 PNES 和 ES 并提供有效治疗时,应更加关注人格障碍。