Kanaev S V, Novikov S N, Zhukova L A, Zotova O V, Semiglazov V F, Krivorot'ko P V
Vopr Onkol. 2011;57(5):616-21.
Determination of lymph flow from breast cancer can be used as effective tool for individualization of radiation portals for regional radiotherapy. We evaluated this technique in 86 patients with lymph nodes (LN) scintigraphy which was performed 20-240 min after intratumoural injection of 50-100 MBq of 99mTc-nanocolloids. After visualisation of lymph flow patterns standard radiation portals were modified in 75% of patients with external and 85%--with internal localisation of primary tumours, In addition we recognised that extent and wideness of radiation portals for internal mammary lymph LN must be arranged in accordance with individual lymph flow pattern. In particularly irradiation of LN on both sides of the sternum was performed only in 3 of 27 (11%) evaluated cases.
乳腺癌淋巴引流的测定可作为区域放射治疗中个体化放疗野的有效工具。我们对86例患者进行了评估,在瘤内注射50 - 100MBq的99mTc - 纳米胶体后20 - 240分钟进行淋巴结(LN)闪烁显像。在观察到淋巴引流模式后,75%的原发肿瘤位于体表的患者和85%的原发肿瘤位于体内的患者的标准放疗野被修改。此外,我们认识到,内乳淋巴结放疗野的范围和宽度必须根据个体淋巴引流模式进行安排。特别是,在27例评估病例中,仅3例(11%)对胸骨两侧的淋巴结进行了照射。