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中国养老院老年居民 2 年死亡率预测指标的制定与验证。

Development and validation of a prognostic index for 2-year mortality in Chinese older residents living in nursing homes.

机构信息

Department of Medicine and Geriatrics, Fung Yiu King Hospital, Hong Kong, China.

出版信息

Geriatr Gerontol Int. 2012 Jul;12(3):555-62. doi: 10.1111/j.1447-0594.2011.00804.x. Epub 2012 Jan 12.

Abstract

AIM

There is no mortality prediction index for Chinese nursing home older residents. The objective of this study was to derive and validate a 2-year mortality prognostic index for them.

METHODS

We carried out a prospective cohort study on 1120 older residents from 12 nursing homes of Hong Kong. We obtained potential predictors of mortality and carried out updated functional assessment. Each risk factor associated independently with 2-year mortality in a derivation cohort was assigned a score based on the odds ratio, and risk scores were calculated for each participant by adding the points of risk factors present. Similar analysis was carried out on the validation cohort.

RESULTS

Independent predictors of mortality included: aged 86-90 years (3 points); aged ≥ 91 years (4 points); Charlson comorbidity index ≥ 4 (6 points); Barthel Index 5-60 (5 points); Barthel Index 0 (10 points); number of hospitalizations in the preceding year (Adbefore) 1 (4 points); Adbefore 2 (5 points) and Adbefore ≥ 3 (6 points). In the derivation cohort, 2-year mortality was 10.8% in the low-risk group (≤ 4 points) and 59.9% in the high-risk group (≥ 14 points). In the validation cohort, 2-year mortality was 11.8% in the low-risk group and 60.4% in the high-risk group. The receiver-operator characteristic curve area was 0.761 for the derivation cohort and 0.742 for the validation cohort.

CONCLUSIONS

Our prognostic index had satisfactory discrimination and calibration in an independent sample of Chinese nursing home older residents. It can be used to identify older residents with a high risk for poor outcomes, who need a different level of care.

摘要

目的

目前尚无针对中国养老院老年居民的死亡率预测指标。本研究旨在为他们建立并验证一个 2 年死亡率预测指数。

方法

我们对来自香港 12 家养老院的 1120 名老年居民进行了前瞻性队列研究。我们获得了与死亡率相关的潜在预测因素,并进行了最新的功能评估。在推导队列中,与 2 年死亡率独立相关的每个危险因素均根据优势比赋予一个分数,并通过将存在危险因素的分数相加来计算每个参与者的风险评分。在验证队列中进行了类似的分析。

结果

死亡率的独立预测因素包括:年龄 86-90 岁(3 分);年龄≥91 岁(4 分);Charlson 合并症指数≥4(6 分);巴氏量表 5-60(5 分);巴氏量表 0(10 分);前一年住院次数(Adbefore)1(4 分);Adbefore 2(5 分)和 Adbefore≥3(6 分)。在推导队列中,低危组(≤4 分)的 2 年死亡率为 10.8%,高危组(≥14 分)的 2 年死亡率为 59.9%。在验证队列中,低危组的 2 年死亡率为 11.8%,高危组的 2 年死亡率为 60.4%。推导队列的受试者工作特征曲线下面积为 0.761,验证队列的为 0.742。

结论

我们的预后指数在独立的中国养老院老年居民样本中具有良好的区分度和校准度。它可以用于识别预后不良风险较高的老年居民,为他们提供不同水平的护理。

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