[缺血性卒中作为韦格纳肉芽肿病的首发表现]

[Ischemic stroke as the first manifestation of Wegener's granulomatosis].

作者信息

Pasquet F, Karkowski L, Hajek V, Pavic M, Guilloton L

机构信息

Service de médecine interne-oncologie, hôpital d'instruction des armées Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.

出版信息

Rev Med Interne. 2012 Feb;33(2):e6-9. doi: 10.1016/j.revmed.2011.02.003. Epub 2012 Jan 11.

DOI:10.1016/j.revmed.2011.02.003

PMID:22240288

Abstract

The most characteristic clinical manifestations of Wegener's granulomatosis are upper and lower respiratory tract and renal involvement. The central nervous system manifestations are uncommon and occur usually late in the course of the disease. We report a 48-year-old man who presented with an ischemic stroke as the first manifestation of Wegener's granulomatosis. Wegener's granulomatosis should be considered in the differential diagnosis of ischemic stroke even in the absence of extraneurological involvement.

摘要

韦格纳肉芽肿最典型的临床表现是上、下呼吸道及肾脏受累。中枢神经系统表现并不常见，通常出现在疾病后期。我们报告一名48岁男性，以缺血性中风作为韦格纳肉芽肿的首发表现。即使没有神经外受累表现，在缺血性中风的鉴别诊断中也应考虑韦格纳肉芽肿。