神经发生：过早的有丝分裂进入使卵裂面起飞！
Neurogenesis: premature mitotic entry lets cleavage planes take off!
机构信息
Biozentrum, University of Basel, CH-4056 Basel, Switzerland.
出版信息
Curr Biol. 2012 Jan 10;22(1):R25-8. doi: 10.1016/j.cub.2011.11.015.
PMID:22240477
Abstract
Mutations in the gene microcephalin/MCPH1 result in the neurodevelopmental disease microcephaly. A recent report provides evidence that MCPH1 controls neuroprogenitor entry into mitosis via the Chk1-Cdc25b centrosome maturation pathway.
摘要
基因突变导致 microcephalin/MCPH1 基因缺失，从而引发神经发育障碍疾病小头症。最近的一份报告提供了证据，表明 MCPH1 通过 Chk1-Cdc25b 中心体成熟途径控制神经祖细胞进入有丝分裂。
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