[人类实体瘤中原癌基因的激活]
[Proto-oncogenes activation in human solid tumors].
作者信息
Birnbaum D, de Lapeyrière O
机构信息
U 119 INSERM, Marseille, France.
出版信息
Bull Cancer. 1990;77(9):857-75.
PMID:2224159
Abstract
Genetic alterations in solid human tumors occur in several groups of genes, one of which contains the proto-oncogenes. These genes are involved in the control of cell proliferation and become activated in oncogenes by various mechanisms. These activations are reviewed herein.
摘要
人类实体瘤中的基因改变发生在几组基因中，其中一组包含原癌基因。这些基因参与细胞增殖的控制，并通过各种机制在癌基因中被激活。本文对这些激活过程进行综述。
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