Section of Neurosurgery, The University of Chicago Medical Center, 5841 South Maryland Avenue, MC 3026, Chicago, IL 60637, USA.
J Clin Neurosci. 2012 Apr;19(4):610-1. doi: 10.1016/j.jocn.2011.06.022. Epub 2012 Jan 14.
Ocular melanoma is a rare type of malignant melanoma. Melanoma metastatic to the spine typically arises within the vertebral column, presents with back pain, and has a poor prognosis. We present a patient with a unique disease course: ocular melanoma metastasis occurred after an extended latency period of 14 years, attained a large size within the spinal intradural space, presented with severe neurological deficits without additional central nervous system disease, and the tumor was amenable to surgical intervention. We also review the literature on melanoma spine metastasis.
眼黑色素瘤是一种罕见的恶性黑色素瘤。脊柱转移的黑色素瘤通常起源于脊柱内，表现为背痛，预后不良。我们报告了一例具有独特病程的患者：眼黑色素瘤转移发生在 14 年的较长潜伏期之后，在椎管内占据了较大的空间，出现严重的神经功能缺损而无其他中枢神经系统疾病，且肿瘤可通过手术干预。我们还回顾了黑色素瘤脊柱转移的文献。
