Al-Otaibi Faisal, Al-Khairallah Thamer
Division of Neurosurgery, Neurosciences Department, King Faisal Specialist Hospital and Research Centre, Saudi Arabia.
Neurosciences (Riyadh). 2012 Jan;17(1):16-31.
Different complex neuroanatomical and neurochemical circuits regulate a variety of neuronal behaviors and brain functions. Any disturbance in these circuits can generate functional disorders such as movement disorders, epilepsy, pain, memory disorders, and psychiatric disorders. Functional neurosurgery aims to restore these functions, either by removing or isolating the abnormally behaving neurons or by modulating the disturbed circuits. Neuromodulation is a fast-growing field, powered by the recent advances in neuroimaging and technology. Here, we discuss recent advances and new horizons in functional neurosurgery.
不同的复杂神经解剖学和神经化学回路调节着多种神经元行为和脑功能。这些回路中的任何干扰都可能产生功能障碍,如运动障碍、癫痫、疼痛、记忆障碍和精神障碍。功能神经外科旨在通过去除或隔离行为异常的神经元或调节受干扰的回路来恢复这些功能。神经调节是一个快速发展的领域,得益于神经影像学和技术的最新进展。在此,我们讨论功能神经外科的最新进展和新前景。