Health Services Research Centre, Akershus University Hospital, Lørenskog, Norway (KRH, LAA, FAD, KS)
Institute of Psychology, University of Oslo, Oslo, Norway (KRH)
Med Decis Making. 2012 Jul-Aug;32(4):569-77. doi: 10.1177/0272989X11431607. Epub 2012 Jan 12.
EQ-5D valuation studies are usually performed using the time tradeoff (TTO) method, which is costly and time consuming. We focused on 2 properties that particularly characterize TTO: the initial choice task categorizing health states as better than death (BTD), worse than death (WTD), or equal to death (ETD), and unwillingness to trade (UTT) lifetime to improve health. The aim of this study was to estimate the value of the information to be gained from continuing the conventional TTO tasks beyond the initial question and the extent to which mean-based EQ-5D tariff values could be predicted through a simplified method of categorizing health states into BTD, WTD, ETD, and UTT.
We used data from the UK EQ-5D valuation study (n = 2997). We designed an abbreviated system with only 4 values (collapsed TTO [cTTO]) based on the 4 response categories and assigned values as follows: WTD = -.5, ETD = 0, BTD = .5, and UTT = 1. Based on the mean cTTO scores for the valued health states, we created a regression-based cTTO tariff, which was compared with the conventional (full) TTO tariff (fTTO) by regressing 1) the fTTO means on cTTO means and 2) the fTTO tariff on the cTTO tariff.
WTD values were unrelated to health state severity. Correlation between the means of fTTO and means of cTTO was >.999, and tariff values from fTTO correlated with tariff values from cTTO at r > .999.
Once respondents have classified health states as UTT, BTD, ETD, or WTD, the TTO procedure adds little further information to the tariff values. The WTD task fails to discriminate between good and bad health states. TTO valuation could likely be simplified using cTTO.
EQ-5D 价值评估研究通常使用时间权衡 (TTO) 方法进行,该方法成本高且耗时。我们专注于 TTO 特别具有代表性的两个特性:初始选择任务将健康状态分类为优于死亡 (BTD)、劣于死亡 (WTD) 或等同于死亡 (ETD),以及不愿意用寿命来换取健康的改善 (UTT)。本研究的目的是估计从初始问题继续进行传统 TTO 任务所获得的信息的价值,以及通过将健康状态分类为 BTD、WTD、ETD 和 UTT 的简化方法来预测均值为基础的 EQ-5D 关税值的程度。
我们使用了来自英国 EQ-5D 价值评估研究 (n = 2997) 的数据。我们设计了一个仅包含 4 个值的简化系统 (缩短 TTO [cTTO]),基于 4 个反应类别,并赋值如下:WTD = -.5,ETD = 0,BTD =.5,UTT = 1。基于所评估健康状态的平均 cTTO 得分,我们创建了一个基于回归的 cTTO 关税,通过回归 1) fTTO 均值与 cTTO 均值之间的关系和 2) fTTO 关税与 cTTO 关税之间的关系,将其与传统的 (完整) TTO 关税 (fTTO) 进行比较。
WTD 值与健康状态严重程度无关。fTTO 和 cTTO 的均值之间的相关性>.999,并且 fTTO 的关税值与 cTTO 的关税值之间的相关性在 r>.999 时具有相关性。
一旦受访者将健康状态分类为 UTT、BTD、ETD 或 WTD,TTO 程序就不会为关税值增加太多额外信息。WTD 任务未能在健康状态良好和不良之间进行区分。TTO 评估可能可以通过 cTTO 简化。