氢氯噻嗪对降低特发性高钙尿症女孩复发性腹痛的作用。
Effect of hydrochlorothiazide on reducing recurrent abdominal pain in girls with idiopathic hypercalciuria.
作者信息
Yousefi Parsa, Cyrus Ali, Dorreh Fatemeh, Gazerani Nafiseh, Sedigh Hamid Reza
机构信息
Assistant Professor, Department of Pediatrics, Arak University of Medical Science, Arak, Iran.
出版信息
J Res Med Sci. 2011 Mar;16 Suppl 1(Suppl1):S433-6.
BACKGROUND
This study assessed the possible effect of hydrochlorothiazide (HCT) on soothing recurrent abdominal pain (RAP).
METHODS
A hundred girls with RAP and IH were randomly assigned into two groups of experiment (treated with hydrochlorothiazide 1mg/kg/day) and control and all patients were followed for 3 months.
RESULTS
In the experiment group, the mean of painful attacks in the first, second and third month were 0.38, 0.4 and 0.26, respectively which were far less than their counterparts in the control group.
CONCLUSIONS
Single daily dose of HCT is a safe and effective therapeutic option in the treatment of RAP in children with IH.
背景
本研究评估了氢氯噻嗪（HCT）对缓解复发性腹痛（RAP）的可能效果。
方法
将100名患有RAP和肠易激综合征（IH）的女孩随机分为两组，实验组（每天服用1mg/kg的氢氯噻嗪）和对照组，所有患者均随访3个月。
结果
在实验组中，第一个月、第二个月和第三个月的平均疼痛发作次数分别为0.38、0.4和0.26，远低于对照组的相应次数。
结论
每日单次剂量的HCT是治疗患有IH的儿童RAP的一种安全有效的治疗选择。
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