Maratos Eleni C, Trivedi Rikin, Richards Hugh, Seeley Helen, Laing Rodney J C
Department of Neurosurgery, Addenbrooke's Hospital, Cambridge, UK.
Br J Neurosurg. 2012 Aug;26(4):466-71. doi: 10.3109/02688697.2011.644821. Epub 2012 Jan 16.
Physical outcomes following surgery for degenerative spine disease have been well studied whereas the importance of psychological factors has only recently been acknowledged. Previous studies suggest that pre-operative psychological distress predicts poor outcome from spinal surgery. In the drive to identify patients who will not benefit, these patients risk being denied surgery.
This is a prospective series from a spinal surgical register.
The study examines the relationship between the physical symptoms, pre-operative psychological distress and outcome following surgery.
The Short Form 36 (SF36) Health Survey Questionnaire and the Hospital Anxiety and Depression Scale (HADS) were administered to patients undergoing elective surgery for degenerative spine disease pre-operatively and at 3 and 12 months post-operatively. Levels of physical disability (SF-36 physical functioning (SF36PF) and bodily pain (SF36BP) scores) and psychological distress (HADS-anxiety and HADS-depression scores) before and after surgery were compared.
A total of 302 patients were included (169 men, 133 women, mean age 55 years). Pre-operatively patients had worse physical scores than age-matched controls (SF36PF normative mean (S.D.) 80.97 (12.69) vs. pre-op 33.31 (24.7) P < 0.05). Of the 302 patients, 117 (39%) had significant anxiety or depression. Increased levels of anxiety or depression pre-operatively correlated with worse physical (SF-36PF and SF-36BP) scores pre-operatively (Spearman's r P < 0.05). Levels of anxiety and depression were reduced post-operatively and physical outcomes improved post-operatively. Physical function remained worse in those groups who had high levels of anxiety and depression pre-operatively but when matched for pre-operative physical function, psychological distress did not have any additional effect on outcome.
Poor physical function pre-operatively correlates with psychological distress. Both physical and psychological symptoms improve after surgery. Physical outcome after surgery is strongly influenced by pre-operative physical functioning but not independently by psychological distress. Anxious and depressed patients should continue to be offered surgery if clinically indicated.
退行性脊柱疾病手术后的身体预后已得到充分研究,而心理因素的重要性直到最近才得到认可。先前的研究表明,术前心理困扰预示着脊柱手术预后不佳。在努力识别那些无法从手术中获益的患者时,这些患者有被拒绝手术的风险。
这是一项来自脊柱外科登记处的前瞻性系列研究。
本研究探讨身体症状、术前心理困扰与术后预后之间的关系。
对因退行性脊柱疾病接受择期手术的患者在术前、术后3个月和12个月进行简短健康调查问卷36项(SF36)和医院焦虑抑郁量表(HADS)评估。比较手术前后的身体残疾程度(SF - 36身体功能(SF36PF)和身体疼痛(SF36BP)评分)以及心理困扰程度(HADS - 焦虑和HADS - 抑郁评分)。
共纳入302例患者(169例男性,133例女性,平均年龄55岁)。术前患者的身体评分比年龄匹配的对照组差(SF36PF标准均值(标准差)80.97(12.69)vs.术前33.31(24.7),P < 0.05)。在302例患者中,117例(39%)有明显的焦虑或抑郁。术前焦虑或抑郁水平升高与术前较差的身体(SF - 36PF和SF - 36BP)评分相关(Spearman相关系数P < 0.05)。术后焦虑和抑郁水平降低,身体预后改善。术前焦虑和抑郁水平高的组中身体功能仍然较差,但在术前身体功能匹配的情况下,心理困扰对预后没有额外影响。
术前身体功能差与心理困扰相关。手术前后身体和心理症状均有改善。术后身体预后受术前身体功能的强烈影响,而不受心理困扰的独立影响。如果临床有指征,焦虑和抑郁患者仍应接受手术。