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Temozolomide for pediatric high-grade gliomas.

作者信息

Packer Roger J

机构信息

Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, Gilbert Neurofibromatosis Institute, Brain Tumor Institute, 111 Michigan Avenue, NW, Washington, DC 20010, USA.

出版信息

Curr Neurol Neurosci Rep. 2012 Apr;12(2):111-3. doi: 10.1007/s11910-012-0250-2.

DOI:10.1007/s11910-012-0250-2
PMID:22249491
Abstract
摘要

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Temozolomide for pediatric high-grade gliomas.替莫唑胺用于儿童高级别胶质瘤
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Chemoradiotherapy in high-grade gliomas.高级别胶质瘤的放化疗
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Temozolomide during and after radiation therapy for WHO grade III gliomas: preliminary report of a prospective multicenter study.替莫唑胺在世界卫生组织 3 级胶质瘤放疗期间和放疗后的应用：一项前瞻性多中心研究的初步报告。
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Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.替莫唑胺用于儿童新诊断的高级别胶质瘤和预后不良的低级别胶质瘤放疗后治疗
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Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas.对于胶质瘤患者，静脉注射替莫唑胺是比口服替莫唑胺胶囊治疗更有效的替代方案。
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本文引用的文献

1
Treatment of high-grade glioma in children and adolescents.儿童和青少年高级别脑胶质瘤的治疗。
Neuro Oncol. 2011 Oct;13(10):1049-58. doi: 10.1093/neuonc/nor092. Epub 2011 Jul 22.
2
Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group.替莫唑胺治疗新诊断弥漫性内在脑桥胶质瘤患儿：儿童肿瘤学组报告
Neuro Oncol. 2011 Apr;13(4):410-6. doi: 10.1093/neuonc/noq205. Epub 2011 Feb 22.
3
IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group.
异柠檬酸脱氢酶1（IDH1）突变在青少年恶性胶质瘤中很常见：来自儿童肿瘤学组的报告。
Childs Nerv Syst. 2011 Jan;27(1):87-94. doi: 10.1007/s00381-010-1264-1. Epub 2010 Aug 20.
4
Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas.血小板衍生生长因子受体的蛋白表达与儿童胶质瘤的恶性组织学相关，而磷酸酶和张力蛋白同源物（PTEN）的蛋白表达与儿童胶质瘤的生存率相关。
Clin Cancer Res. 2008 Jun 1;14(11):3386-94. doi: 10.1158/1078-0432.CCR-07-1616.
5
Tyrosine kinase expression in pediatric high grade astrocytoma.酪氨酸激酶在儿童高级别星形细胞瘤中的表达
J Neurooncol. 2008 May;87(3):247-53. doi: 10.1007/s11060-007-9513-1. Epub 2008 Jan 10.
6
The 2007 WHO classification of tumours of the central nervous system.2007年世界卫生组织中枢神经系统肿瘤分类
Acta Neuropathol. 2007 Aug;114(2):97-109. doi: 10.1007/s00401-007-0243-4. Epub 2007 Jul 6.
7
O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: results from the CCG-945 Cohort.O6-甲基鸟嘌呤-DNA甲基转移酶表达与儿童恶性胶质瘤的预后密切相关：CCG-945队列研究结果
J Clin Oncol. 2006 Jul 20;24(21):3431-7. doi: 10.1200/JCO.2006.05.7265.
8
MGMT gene silencing and benefit from temozolomide in glioblastoma.MGMT基因沉默与胶质母细胞瘤对替莫唑胺的获益
N Engl J Med. 2005 Mar 10;352(10):997-1003. doi: 10.1056/NEJMoa043331.
9
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.放疗联合同步及辅助替莫唑胺治疗胶质母细胞瘤
N Engl J Med. 2005 Mar 10;352(10):987-96. doi: 10.1056/NEJMoa043330.
10
Supratentorial high-grade astrocytoma and diffuse brainstem glioma: two challenges for the pediatric oncologist.幕上高级别星形细胞瘤和弥漫性脑干胶质瘤：儿科肿瘤学家面临的两大挑战。
Oncologist. 2004;9(2):197-206. doi: 10.1634/theoncologist.9-2-197.