Galera Llorca Jordi, Lahoz Grillo Raquel, Roig Loscertales Francesc
Health Outcomes Research, Novartis Farmacéutica, Barcelona, España.
Rev Esp Salud Publica. 2011 Dec;85(6):583-91. doi: 10.1590/S1135-57272011120000007.
Deficiencies detected in biomedical studies publication different Guidelines to improve. The objective of the study is to assess the communication of observational studies of Cardiovascular and Metabolism therapeutic area (CVM) published in 6 Spanish journals in 2009 using the STROBE statement.
Cross-sectional analysis of articles related to CVM therapeutic area, published during 2009 in 6 Spanish journals applying the 34 items of the STROBE statement. Descriptive analysis of the results for qualitative variables was performed using a frequency analysis. Quantitative variables were analyzed by sample estimates and dispersion. A comparative analysis of journals was performed using ANOVA with a statistical significance of p<0.05.
Throughout 2009, 74 CVM observational studies were published in the evaluated journals. The most frequent design were cohorts 45 (60.8%) and cross-sectional 28 (37.8%). The study main objective was on pathology 55 (74.3%), followed by drug and non-pharmacological interventions 15 (20.3%) and diagnosis 4 (5.4%). The mean of complied items was 20 on 34 (DE±3.7), with a maximum of 24 (DE±2) in Gaceta Sanitaria and a minimum of 19 (DE±2.8) in Hipertensión.
Evaluated papers comply with slightly more than a half items (58%) of the STROBE recommendations. The Methods and Results sections showed more deficiencies.
生物医学研究出版物中发现存在不足，需要不同的指南来改进。本研究的目的是使用STROBE声明评估2009年发表在6种西班牙期刊上的心血管和代谢治疗领域（CVM）观察性研究的报告情况。
对2009年发表在6种西班牙期刊上的与CVM治疗领域相关的文章进行横断面分析，应用STROBE声明的34项内容。对定性变量的结果进行描述性分析时采用频率分析。对定量变量进行样本估计和离散分析。使用方差分析对期刊进行比较分析，统计学显著性为p<0.05。
2009年全年，在评估的期刊上发表了74项CVM观察性研究。最常见的设计是队列研究45项（60.8%）和横断面研究28项（37.8%）。研究的主要目的是病理学55项（74.3%），其次是药物和非药物干预15项（20.3%）以及诊断4项（5.4%）。符合的项目平均为34项中的20项（均值±3.7），《卫生公报》中最多为24项（均值±2），《高血压》中最少为19项（均值±2.8）。
评估的论文符合STROBE建议略多于一半的项目（58%）。方法和结果部分显示出更多不足。
