Department of Radiology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, Wakayama, 641-8510, Japan.
Jpn J Radiol. 2012 May;30(4):358-64. doi: 10.1007/s11604-011-0048-1. Epub 2012 Jan 17.
To explore the optimal contrast material (CM) concentration for distinguishing CM, carotid stent (CS), and neck components in cone-beam computed tomography (CBCT) during carotid angiography (CBCT-CA).
A neck phantom containing CS and contrast-filled imitation vessels of 9 mm diameter was scanned using CBCT. CM (300 mgI/ml) was used in concentrations of 100, 50, 33, 10, 5, and 1%. In a clinical study, 30 patients with a CS (Precise or Wallstent) underwent CBCT-CA with CM injected at a rate of 3 ml/s and a concentration of 10 or 20%.
In the basic study, CBCTA using 5% CM enabled clear distinction among the three components under windowing at 1500 width and 300 center, and showed the exact diameter of the imitation vessel. Pixel values of CM inside the Precise and the Wallstent were 622.2 ± 32.9 (mean ± SD) and 746.0 ± 27.9, respectively. In the clinical study using CM at concentrations of 10 and 20%, pixel values of CM inside the Wallstent were 632.3 ± 69.2 and 1024.5 ± 99.0, respectively.
Optimal CM concentration for distinguishing among the three components was 5% in the basic study; the optimal concentration was 10% in the clinical study.
探讨颈动脉血管造影锥形束 CT（CBCT-CA）中区分对比剂（CM）、颈动脉支架（CS）和颈部结构的最佳 CM 浓度。
使用 CBCT 对含有 CS 和 9 毫米直径 CM 充盈模拟血管的颈部模型进行扫描。CM（300mgI/ml）浓度分别为 100%、50%、33%、10%、5%和 1%。在一项临床研究中，30 例植入 Precise 或 Wallstent 的患者以 3ml/s 的速度和 10%或 20%的浓度注射 CM 进行 CBCT-CA。
在基础研究中，使用 5%的 CM 在窗宽 1500 和窗位 300 下可以清晰地区分三个成分，并且可以显示模拟血管的准确直径。Precise 和 Wallstent 内 CM 的像素值分别为 622.2±32.9（均值±标准差）和 746.0±27.9。在使用浓度为 10%和 20%的 CM 的临床研究中，Wallstent 内 CM 的像素值分别为 632.3±69.2 和 1024.5±99.0。
在基础研究中，区分三个成分的最佳 CM 浓度为 5%；在临床研究中，最佳浓度为 10%。
