脊髓小脑共济失调的耳神经学表现

Otoneurological findings in spinocerebellar ataxia.

作者信息

Zeigelboim Bianca S, Ghizoni Teive Hélio A, Sampaio Rosane, Arruda Walter O, Jurkiewicz Ari L, Marques Jair M, Klagemberg Karlin F, Mengelberg Heidi, Liberalesso Paulo Breno Noronha

机构信息

Tuiuti University of Parana, Curitiba, Brazil.

出版信息

Int Tinnitus J. 2011;16(2):161-7.

PMID:22249876

Abstract

OBJECTIVE

Describe findings observed in ENG of patients with spinocerebellar ataxias.

METHOD

Forty-three patients were studied, and the following procedures were carried out: anamnesis, otorhinolaryngological and vestibular evaluation (ENG).

RESULTS

The clinical findings in the entire group of patients were: gait disturbances (83.72%), speech difficulties (48.83%), dizziness (41.86%) and dysphagia (39.53%). Vestibular examination disclosed abnormal caloric exam (83.71%) and saccadic movements (69.76%) with the highest rates of abnormality. The overall presence of alterations in vestibular tests was (90.70%), and the most frequent finding was central vestibular disorder in (74.42%) of patients.

CONCLUSION

The study showed that alterations in ENG are related to the severity of SCAs or clinical stage of the disease. We emphasize the importance of studying the vestibular system concomitantly to clinical and genetic follow up.

摘要

目的

描述脊髓小脑共济失调患者眼震电图（ENG）的观察结果。

方法

对43例患者进行研究，并开展了以下检查：问诊、耳鼻喉科及前庭评估（ENG）。

结果

整组患者的临床症状为：步态障碍（83.72%）、言语困难（48.83%）、头晕（41.86%）及吞咽困难（39.53%）。前庭检查显示异常冷热试验（83.71%）和扫视运动（69.76%），异常率最高。前庭检查中改变的总体发生率为（90.70%），最常见的发现是74.42%的患者存在中枢性前庭障碍。