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新型便携式体外膜肺氧合系统Cardiohelp用于成人严重呼吸衰竭的首次经验。

First experience with the new portable extracorporeal membrane oxygenation system Cardiohelp for severe respiratory failure in adults.

作者信息

Haneya A, Philipp A, Foltan M, Camboni D, Müeller T, Bein T, Schmid C, Lubnow M

机构信息

Dept. of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany.

出版信息

Perfusion. 2012 Mar;27(2):150-5. doi: 10.1177/0267659111432330. Epub 2012 Jan 16.

Abstract

BACKGROUND

Over the last decade, technical improvements in extracorporeal membrane oxygenation (ECMO) equipment have reduced procedure-related complications and have made ECMO an effective option for patients with acute respiratory distress syndrome (ARDS) if conventional therapy fails.

METHODS

In this report, we present our early experience with the Cardiohelp, a new portable miniaturized ECMO system, in 22 consecutive patients with ARDS. All patients were placed on venovenous ECMO. Cannulas were inserted percutaneously, employing the Seldinger technique. Data were collected prospectively.

RESULTS

The median patient age was 47 years (36 to 61). Fifteen patients from regional hospitals were too unstable for conventional transport and were placed on Cardiohelp at the referring hospital and then transported to our institution. The patients were transported by ambulance (n=2) or helicopter (n=13) over a distance of 50-250 km. Cardiohelp support resulted in immediate improvement of gas exchange and highly protective ventilation. The median duration of support was 13 days (8 to 19). An exchange of the device was necessary in 9 patients. Sixteen patients (72.7%) were successfully weaned from ECMO and fifteen patients (68.2%) survived. Device-related complications were not observed.

CONCLUSIONS

The compact portable ECMO device Cardiohelp is a highly effective method to secure vital gas exchange and to reduce further ventilator-induced lung injury in patients with acute respiratory failure. Crucial technical innovations and ease of device transport and implantation allow location-independent stabilization with consecutive inter-hospital transfer.

摘要

背景

在过去十年中,体外膜肺氧合(ECMO)设备的技术改进减少了与操作相关的并发症,并且如果传统治疗失败,ECMO已成为急性呼吸窘迫综合征(ARDS)患者的有效选择。

方法

在本报告中,我们介绍了我们对一种新型便携式小型ECMO系统Cardiohelp在22例连续ARDS患者中的早期经验。所有患者均接受静脉-静脉ECMO治疗。采用Seldinger技术经皮插入插管。前瞻性收集数据。

结果

患者中位年龄为47岁(36至61岁)。15例来自地区医院的患者病情过于不稳定,无法进行传统转运,在转诊医院接受Cardiohelp治疗,然后转运至我们的机构。患者通过救护车(n = 2)或直升机(n = 13)转运,转运距离为50 - 250公里。Cardiohelp支持导致气体交换立即改善,并实现了高度保护性通气。中位支持时间为13天(8至19天)。9例患者需要更换设备。16例患者(72.7%)成功脱机,15例患者(68.2%)存活。未观察到与设备相关的并发症。

结论

紧凑型便携式ECMO设备Cardiohelp是确保急性呼吸衰竭患者重要气体交换并减少进一步呼吸机诱导性肺损伤的高效方法。关键的技术创新以及设备易于运输和植入使得在不同地点实现稳定,并可进行连续的院间转运。

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