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美国入境难民儿童铅中毒:2009 年泰国-缅甸边境。

Lead poisoning in United States-bound refugee children: Thailand-Burma border, 2009.

机构信息

Division of Global Migration, Immigrant, Refugee, and Migrant Health Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.

出版信息

Pediatrics. 2012 Feb;129(2):e392-9. doi: 10.1542/peds.2011-1218. Epub 2012 Jan 16.

Abstract

BACKGROUND

Elevated blood lead levels lead to permanent neurocognitive sequelae in children. Resettled refugee children in the United States are considered at high risk for elevated blood lead levels, but the prevalence of and risk factors for elevated blood lead levels before resettlement have not been described.

METHODS

Blood samples from children aged 6 months to 14 years from refugee camps in Thailand were tested for lead and hemoglobin. Sixty-seven children with elevated blood lead levels (venous ≥10 µg/dL) or undetectable (capillary <3.3 µg/dL) blood lead levels participated in a case-control study.

RESULTS

Of 642 children, 33 (5.1%) had elevated blood lead levels. Children aged <2 years had the highest prevalence (14.5%). Among children aged <2 years included in a case-control study, elevated blood lead levels risk factors included hemoglobin <10 g/dL, exposure to car batteries, and taking traditional medicines.

CONCLUSIONS

The prevalence of elevated blood lead levels among tested US-bound Burmese refugee children was higher than the current US prevalence, and was especially high among children <2 years old. Refugee children may arrive in the United States with elevated blood lead levels. A population-specific understanding of preexisting lead exposures can enhance postarrival lead-poisoning prevention efforts, based on Centers for Disease Control and Prevention recommendations for resettled refugee children, and can lead to remediation efforts overseas.

摘要

背景

血液中铅含量升高会对儿童的神经认知造成永久性损害。在美国,重新安置的难民儿童被认为存在血液铅含量升高的高风险,但在重新安置之前,血液铅含量升高的流行情况和风险因素尚未得到描述。

方法

对来自泰国难民营的 6 个月至 14 岁儿童的血液样本进行铅和血红蛋白检测。67 名血液铅含量升高(静脉血≥10μg/dL)或检测不到(毛细血管<3.3μg/dL)的儿童参与了病例对照研究。

结果

在 642 名儿童中,有 33 名(5.1%)血液铅含量升高。年龄<2 岁的儿童患病率最高(14.5%)。在包括在病例对照研究中的年龄<2 岁的儿童中,血液铅含量升高的危险因素包括血红蛋白<10g/dL、接触汽车电池和服用传统药物。

结论

接受检测的即将前往美国的缅甸难民儿童中血液铅含量升高的患病率高于当前美国的患病率,尤其是 2 岁以下儿童的患病率更高。难民儿童可能在抵达美国时就已经血液铅含量升高。根据疾病控制与预防中心对重新安置的难民儿童的建议,了解特定人群的先前铅暴露情况可以加强抵达后的铅中毒预防工作,并可以在海外开展补救工作。

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