Miyazato Akiko, Ohkusu Kiyohumi, Ishii Shunsuke, Sasaoka Taishi, Ikeda Masahiro, Niinami Hiroshi, Ezaki Takayuki, Mitsutake Kotaro
Department of Infectious Diseases and Infection Control, Saitama International Medical Center, Saitama Medical University.
Kansenshogaku Zasshi. 2011 Nov;85(6):678-81. doi: 10.11150/kansenshogakuzasshi.85.678.
Aerococcus urinae is a endocarditis rare causative organism with low virulene. We report an A. urinae endocarditis case treated by aortic valve replacement. An 80-year-old woman hospitalized for urinary tract infection and hydronephrosis due to three-week renal calculi. Blood culture on admission isolated Streptococcus acidominimus. During the course, she was transferred to our care for surgical intervention after developing congestive heart failure due to severe aortic regurgitation. Echocardiographic findings indicated infective endocarditis. She underwent aortic valve replacement, and gram staining of the resected valve tissue showed gram-positive cocci, although valve culture was negative. PCR amplification and DNA sequencing using the valve material matched an A. urinae sequence. The woman recovered and was discharged six weeks after antibiotic treatment.
尿液气球菌是一种毒力低、引起心内膜炎罕见的病原体。我们报告一例经主动脉瓣置换术治疗的尿液气球菌心内膜炎病例。一名80岁女性因三周的肾结石导致尿路感染和肾积水住院。入院时血培养分离出嗜酸微球菌。在此期间,由于严重主动脉瓣反流导致充血性心力衰竭,她被转至我们科室接受手术干预。超声心动图检查结果提示感染性心内膜炎。她接受了主动脉瓣置换术,切除的瓣膜组织革兰氏染色显示革兰氏阳性球菌,尽管瓣膜培养结果为阴性。使用瓣膜材料进行PCR扩增和DNA测序与尿液气球菌序列匹配。该女性在抗生素治疗六周后康复出院。