[Prostanoids and leukotrienes in ophthalmology. III. Results of a clinical study of local administration of indomethacin in preoperative and postoperative care].

The authors submit results of the clinical investigation involving indomethacin administration during preoperative and postoperative care of patients with primary glaucoma who were submitted to trabeculectomy. The investigation was made by the method of a double blind trial. Indomethacin 0.5% eye drops or placebo were administered on the day prior to operation to the 10th day after operation, three times a day. During the final comparison of the two groups after indomethacin a reduction of the number of postoperative complications was observed, as well as a shorter hospitalization period, and the result of the filtering operation was not affected.