真空辅助闭合疗法在阴式切除术患者中的应用。

Vacuum-assisted closure therapy in the management of patients undergoing vulvectomy.

机构信息

Cancer Center-Centre Oscar Lambret, 3 rue Frédéric Combemale, Lille Cedex, France.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2012 Apr;161(2):199-201. doi: 10.1016/j.ejogrb.2011.12.016. Epub 2012 Jan 16.

DOI:10.1016/j.ejogrb.2011.12.016

PMID:22252048

Abstract

OBJECTIVES

To investigate whether systematic postoperative VAC therapy could improve vulvectomy healing.

STUDY DESIGN

We reviewed medical data from 54 women who underwent in the period of March 2006 to December 2009 radical vulvectomy or wide local vulvectomy with defect volume >40cm(3). Patients were divided into two groups according to immediate postoperative care. Patients treated with systematic vacuum-assisted closure (VAC) therapy immediately after surgery were included in the "VAC group" while patients receiving conventional care (CC) were included in the "CC group".

RESULTS

The characteristics of the VAC group (n=30) and CC group (n=24) were similar and there were no significant differences in operative data, histological results or oncologic follow-up. The median length of use of VAC was 11 days after surgery (6-38). The length of hospital stay for patients in the VAC group and CC group was 17.8 (±8.7) and 18.4 days (±9.9) (p=0.8) respectively. The lengths of complete healing were 44.4 (±18.4) vs. 60.2 (±28.7) days (p=0.0175) respectively.

CONCLUSIONS

In our study we proved that using VAC dressing immediately after vulvectomy (at least 6cm×7cm) for 11 days reduces the total length of cicatrization by approximately 16 days.

摘要

目的

研究系统的术后负压辅助闭合（VAC）治疗是否能改善外阴切除术的愈合。

研究设计

我们回顾了 2006 年 3 月至 2009 年 12 月期间接受根治性外阴切除术或广泛局部外阴切除术（缺损体积>40cm³）的 54 名女性的医疗数据。根据术后即刻护理将患者分为两组。术后立即接受系统 VAC 治疗的患者纳入“VAC 组”，接受常规护理（CC）的患者纳入“CC 组”。

结果

VAC 组（n=30）和 CC 组（n=24）的特征相似，手术数据、组织学结果或肿瘤学随访均无显著差异。VAC 术后使用中位数为 11 天（6-38 天）。VAC 组和 CC 组的住院时间分别为 17.8（±8.7）天和 18.4（±9.9）天（p=0.8）。完全愈合的长度分别为 44.4（±18.4）天和 60.2（±28.7）天（p=0.0175）。