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多普勒超声与 D-二聚体:敌友?

Doppler ultrasound and D-dimer: friend or foe?

机构信息

Division of Angiology and Hemostasis, University Hospitals of Geneva, Geneva, Switzerland.

出版信息

Hamostaseologie. 2012;32(1):28-36. doi: 10.5482/ha-1182.

DOI:10.5482/ha-1182
PMID:22252568
Abstract

The diagnosis of venous thromboembolism has evolved considerably with the development of standardized diagnostic algorithms that include clinical probability assessment, D-dimer measurement and the use of non-invasive imaging modalities such as compression ultrasonography and computed tomography angiography. The implementation of these strategies aims to improve resource allocation and patient outcome. The judicious use of these diagnostic tools requires a thorough knowledge of the appropriate clinical setting in which every test and strategy is efficient and can be used safely. For this purpose, D-dimer measurement and compression ultrasonography are complementary: the former is mainly used to exclude VTE in selected patients, while the latter is used to confirm the presence of an underlying DVT. This review provides an appraisal of the features and use of D-dimer and compression ultrasonography in the context of suspected venous thromboembolism.

摘要

静脉血栓栓塞症的诊断随着标准化诊断算法的发展有了显著的进步,这些算法包括临床可能性评估、D-二聚体测量以及使用非侵入性成像方式如压缩超声和计算机断层血管造影。这些策略的实施旨在改善资源分配和患者预后。明智地使用这些诊断工具需要对每种测试和策略在适当的临床环境中有效且安全使用的知识有透彻的了解。为此,D-二聚体测量和压缩超声是互补的:前者主要用于在选定的患者中排除 VTE,而后者用于确认潜在的 DVT 的存在。本综述评估了 D-二聚体和压缩超声在疑似静脉血栓栓塞症中的特征和应用。

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Secular trends in occurrence of acute venous thromboembolism: the Worcester VTE study (1985-2009).静脉血栓栓塞症发生率的长期变化趋势:伍斯特静脉血栓栓塞症研究(1985-2009)。
Am J Med. 2014 Sep;127(9):829-39.e5. doi: 10.1016/j.amjmed.2014.03.041. Epub 2014 May 6.