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经阴道超声、超声造影与磁共振成像诊断深部浸润型子宫内膜异位症的对比研究。

Comparison between transvaginal sonography, saline contrast sonovaginography and magnetic resonance imaging in the diagnosis of posterior deep infiltrating endometriosis.

机构信息

Department of Gynaecological Sciences and Human Reproduction, University of Padova, Padova, Italy.

出版信息

Ultrasound Obstet Gynecol. 2012 Oct;40(4):464-9. doi: 10.1002/uog.11102. Epub 2012 Sep 17.

DOI:10.1002/uog.11102
PMID:22253192
Abstract

OBJECTIVE

To compare clinical evaluation, transvaginal sonography (TVS), saline contrast sonovaginography (SCSV) and magnetic resonance imaging (MRI) in the diagnosis of posterior deep pelvic endometriosis (DPE).

METHODS

Women suspected of having posterior DPE on the basis of subjective symptoms and clinical evaluation underwent digital vaginal and rectal examination, TVS, SCSV and MRI. Laparoscopy was performed and specimens were sent for histological examination. Sensitivity, specificity, positive and negative predictive value, as well as positive and negative likelihood ratios were analyzed for each diagnostic method.

RESULTS

Fifty-four out of 102 women suspected of having posterior DPE underwent laparoscopic surgery. Among these, in 46 (85.2%) cases DPE was confirmed at laparoscopic and histological examination. SCSV correctly identified 43 (93.5%) cases, presenting higher accuracy than did the other procedures. SCSV and MRI were more accurate in diagnosing and discriminating between the different locations of endometriotic lesions, with respective sensitivities of 94.7 and 73.1% for vaginal fornix, 88.9 and 66.7% for the uterosacral ligaments and 80.6 and 83.3% for involvement of the rectovaginal septum. The specificity of SCSV and MRI, respectively, was 97.1 and 94.3% for vaginal fornix, 95.6 and 95.6% for uterosacral ligaments and 100 and 77.8% for involvement of the rectovaginal septum. In the diagnosis of rectal endometriosis, we found a sensitivity of 66.7% for both techniques and specificity of 93.8% for SCSV and 95.8% for MRI.

CONCLUSION

TVS should be used as the first-line diagnostic technique and SCSV and/or MRI as second-line methods in the diagnosis of posterior DPE.

摘要

目的

比较临床评估、经阴道超声(TVS)、盐水对比经阴道超声(SCSV)和磁共振成像(MRI)在诊断深部后盆腔子宫内膜异位症(DPE)中的作用。

方法

基于主观症状和临床评估,对疑似患有深部后盆腔子宫内膜异位症的女性进行数字阴道和直肠检查、TVS、SCSV 和 MRI。腹腔镜检查,并将标本送检进行组织学检查。对每种诊断方法的敏感性、特异性、阳性和阴性预测值以及阳性和阴性似然比进行分析。

结果

102 例疑似患有深部后盆腔子宫内膜异位症的女性中,54 例行腹腔镜手术。其中,46 例(85.2%)腹腔镜和组织学检查证实为深部后盆腔子宫内膜异位症。SCSV 正确诊断 43 例(93.5%),准确率高于其他检查方法。SCSV 和 MRI 在诊断和区分不同部位的子宫内膜异位病变方面更为准确,阴道穹窿的敏感性分别为 94.7%和 73.1%,子宫骶骨韧带为 88.9%和 66.7%,直肠阴道隔为 80.6%和 83.3%。SCSV 和 MRI 的特异性分别为阴道穹窿 97.1%和 94.3%,子宫骶骨韧带 95.6%和 95.6%,直肠阴道隔 100%和 77.8%。直肠子宫内膜异位症的诊断中,两种技术的敏感性均为 66.7%,SCSV 的特异性为 93.8%,MRI 的特异性为 95.8%。

结论

TVS 应作为诊断深部后盆腔子宫内膜异位症的一线诊断技术,SCSV 和/或 MRI 作为二线方法。

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