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一种基于向量心电图的心肌梗死检测分类系统。

A vectorcardiogram-based classification system for the detection of Myocardial infarction.

作者信息

Huang Chih-Sheng, Ko Li-Wei, Lu Shao-Wei, Chen Shi-An, Lin Chin-Teng

机构信息

Brain Research Center and Institute of Electrical Control Engineering, National Chiao Tung University, Hsinchu, Taiwan.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:973-6. doi: 10.1109/IEMBS.2011.6090220.

Abstract

Myocardial infarction (MI), generally known as a heart attack, is one of the top leading causes of mortality in the world. In clinical diagnosis, cardiologists generally utilize 12-lead ECG system to classify patients into MI symptoms: 1. ST segment elevation, 2. ST segment depression or T wave inversion. However unstable ischemic syndromes have rapidly changing supply versus demand characteristics that is one of the several limitations of 12-lead ECG system for MI detection. In addition, the ECG sensor placements of 12-lead system is not easily donned and doffed for tele-healthcare monitoring at home. Vectorcardiogram (VCG) system in clinic is another type of diagnosis plot which represents the magnitude and direction of the electrical potential in the form of a vector loop during cardiac electric activity. The VCG system can easily acquire three ECG waves from X, Y, Z directions to composite vector signal in space and the VCG signals can be transferred to 12-lead ECG signal through Dower transformation and vice versa. Hence, this study attempts to develop a VCG-based classification system for the detection of Myocardial infarction. In the experiment results, the proposed system can select the proper ECG features based on cardiologist's knowledge and proposed principal moments of QRS complex. The classification performance of MI detection can be reached to 99.89% of sensitivity, 92.51% of specificity, 95.35% of positive predictive value, and 96.96% overall accuracy with maximum-likelihood classifier (MLC).

摘要

心肌梗死(MI),通常被称为心脏病发作,是全球主要的致死原因之一。在临床诊断中,心脏病专家通常利用12导联心电图系统将患者分为心肌梗死症状类型:1. ST段抬高;2. ST段压低或T波倒置。然而,不稳定缺血综合征具有快速变化的供需特征,这是12导联心电图系统用于心肌梗死检测的若干局限性之一。此外,12导联系统的心电图传感器放置方式不易于在家中进行远程医疗监测时穿戴和取下。临床中的向量心电图(VCG)系统是另一种诊断图,它以向量环的形式表示心脏电活动期间电位的大小和方向。VCG系统可以轻松地从X、Y、Z方向获取三个心电图波,以合成空间中的向量信号,并且VCG信号可以通过道尔变换转换为12导联心电图信号,反之亦然。因此,本研究试图开发一种基于VCG的心肌梗死检测分类系统。在实验结果中,所提出的系统可以根据心脏病专家的知识和所提出的QRS波群主矩选择合适的心电图特征。使用最大似然分类器(MLC)时,心肌梗死检测的分类性能可达到99.89%的灵敏度、92.51%的特异度、95.35%的阳性预测值和96.96%的总体准确率。

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