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一名患有溃疡性结肠炎、格雷夫斯病且髓过氧化物酶抗中性粒细胞胞浆抗体呈阳性的患者的IgA肾病。

IgA nephropathy in a patient with ulcerative colitis, Graves' disease and positive myeloperoxidase ANCA.

作者信息

Ku Elaine, Ananthapanyasut Wanwarat, Campese Vito M

机构信息

Department of Medicine, Division of Nephrology, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA.

出版信息

Clin Nephrol. 2012 Feb;77(2):146-50. doi: 10.5414/CN106770.

Abstract

We report a case of a 38-year old woman with a history of ulcerative colitis and Graves' disease who presented with pyoderma gangrenosum, microscopic hematuria, proteinuria, and positive myeloperoxidase ANCA. A renal biopsy revealed a focal proliferative glomerulonephritis with IgA deposits. All these manifestations are likely secondary to ulcerative colitis or to a common pathogenetic mechanism.

摘要

我们报告一例38岁女性,有溃疡性结肠炎和格雷夫斯病病史,出现坏疽性脓皮病、镜下血尿、蛋白尿及髓过氧化物酶抗中性粒细胞胞浆抗体(MPO-ANCA)阳性。肾活检显示局灶增生性肾小球肾炎伴IgA沉积。所有这些表现可能继发于溃疡性结肠炎或共同的发病机制。

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