Ku Elaine, Ananthapanyasut Wanwarat, Campese Vito M
Department of Medicine, Division of Nephrology, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA.
Clin Nephrol. 2012 Feb;77(2):146-50. doi: 10.5414/CN106770.
We report a case of a 38-year old woman with a history of ulcerative colitis and Graves' disease who presented with pyoderma gangrenosum, microscopic hematuria, proteinuria, and positive myeloperoxidase ANCA. A renal biopsy revealed a focal proliferative glomerulonephritis with IgA deposits. All these manifestations are likely secondary to ulcerative colitis or to a common pathogenetic mechanism.
我们报告一例38岁女性,有溃疡性结肠炎和格雷夫斯病病史,出现坏疽性脓皮病、镜下血尿、蛋白尿及髓过氧化物酶抗中性粒细胞胞浆抗体(MPO-ANCA)阳性。肾活检显示局灶增生性肾小球肾炎伴IgA沉积。所有这些表现可能继发于溃疡性结肠炎或共同的发病机制。