Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
J Hum Hypertens. 2013 Feb;27(2):126-30. doi: 10.1038/jhh.2011.116. Epub 2012 Jan 19.
Lifestyle modifications to reduce risk factors for cardiovascular diseases such as blood pressure (BP) and smoking have been emphasized. Fruits and vegetables may modify such risk factors. The major aim of this randomized, controlled trial was to investigate the effects of (1) kiwifruits and (2) an antioxidant-rich diet compared with (3) a control group on BP and platelet aggregation (that is, whole-blood platelet aggregation) after 8 weeks in male smokers (age 44-74 years, n=102). The kiwifruit group received 3 kiwifruits per day, whereas the antioxidant-rich diet group received a comprehensive combination of antioxidant-rich foods. In the kiwifruit group, reductions of 10 mm Hg in systolic BP and 9 mm Hg in diastolic BP were observed (P=0.019 and P=0.016 (change from baseline in the kiwifruit group compared with change from baseline in the control group)). In the antioxidant-rich diet group, a reduction of 10 mm Hg in systolic BP was observed among hypertensives (P=0.045). Additionally, a 15% reduction in platelet aggregation and an 11% reduction in angiotensin-converting enzyme activity was observed in the kiwifruit group (P=0.009 and P=0.034). No effects on these parameters were observed in the antioxidant-rich diet group. This study suggest that intake of kiwifruit may have beneficial effects on BP and platelet aggregation in male smokers.
生活方式的改变，如降低血压（BP）和吸烟等心血管疾病的危险因素，已得到强调。水果和蔬菜可能会改变这些危险因素。本随机对照试验的主要目的是调查（1）奇异果和（2）富含抗氧化剂的饮食与（3）对照组在 8 周后对男性吸烟者（年龄 44-74 岁，n=102）的 BP 和血小板聚集（即全血血小板聚集）的影响。奇异果组每天食用 3 个奇异果，而富含抗氧化剂的饮食组则接受富含抗氧化剂的综合食物组合。在奇异果组中，收缩压降低了 10mmHg，舒张压降低了 9mmHg（P=0.019 和 P=0.016（与对照组相比，奇异果组从基线开始的变化））。在富含抗氧化剂的饮食组中，高血压患者的收缩压降低了 10mmHg（P=0.045）。此外，奇异果组的血小板聚集减少了 15%，血管紧张素转换酶活性减少了 11%（P=0.009 和 P=0.034）。富含抗氧化剂的饮食组对这些参数没有影响。这项研究表明，男性吸烟者摄入奇异果可能对 BP 和血小板聚集有有益的影响。
