Shperling I D, Arakelian L A
L.A. Oganesian Institute of Cardiology, Yerevan, USSR.
Cor Vasa. 1990;32(4):327-34.
Using a modified method for alkalic dissociation, isolated ventricular cardiomyocytes were obtained from eight patients who had died of different diseases. The absolute number of cardiomyocytes, counted in the Fuchs-Rosenthal chamber, ranged between 1.10 x 10(9) and 3.25 x 10(9) in the left ventricle, and between 0.58 x 10(9) and 1.42 x 10(9) in the right ventricle depending on myocardial mass. Mean volume of cells ranged between 75 x 10(3) and 344 x 10(3) microns3, and the content of polynuclear, predominantly binucleated, cardiomyocytes amounted to 14 to 49%. An increase in ventricular myocardium mass was associated with an increase in cardiomyocyte volume. A negative correlation was demonstrated between the absolute number of cardiomyocytes on the one hand, and their mean volume and proportion of polynuclear cells on the other.
采用改良的碱解离方法，从8例死于不同疾病的患者中获取分离的心室心肌细胞。在富克斯-罗森塔尔计数板中计数的心肌细胞绝对数量，左心室介于1.10×10⁹至3.25×10⁹之间，右心室介于0.58×10⁹至1.42×10⁹之间，具体取决于心肌质量。细胞平均体积介于75×10³至344×10³立方微米之间，多核（主要是双核）心肌细胞的含量为14%至49%。心室心肌质量的增加与心肌细胞体积的增加相关。一方面，心肌细胞的绝对数量与另一方面它们的平均体积和多核细胞比例之间呈负相关。
