Ussher Michael H, Taylor Adrian, Faulkner Guy
Division of PopulationHealth Sciences and Education, StGeorge’s,University of London,CranmerTerrace, London, SW17 0RE, UK.
Cochrane Database Syst Rev. 2012 Jan 18;1:CD002295. doi: 10.1002/14651858.CD002295.pub4.
Taking regular exercise may help people give up smoking by moderating nicotine withdrawal and cravings, and by helping to manage weight gain.
To determine whether exercise-based interventions alone, or combined with a smoking cessation programme, are more effective than a smoking cessation intervention alone.
In July 2011, we searched the Cochrane Tobacco Addiction Group Specialized Register for studies including the terms 'exercise' or 'physical activity'. We also searched MEDLINE, EMBASE, PsycINFO, Dissertation Abstracts and CINAHL using the terms 'exercise' or 'physical activity' and 'smoking cessation'.
We included randomized trials which compared an exercise programme alone, or an exercise programme as an adjunct to a cessation programme, with a cessation programme, recruiting smokers or recent quitters, and with a follow up of six months or more.
We extracted data on study characteristics and smoking outcomes. Because of differences in studies we summarized the results narratively, making no attempt at meta-analysis.
We identified 15 trials, seven of which had fewer than 25 people in each treatment arm. They varied in the timing and intensity of the smoking cessation and exercise programmes. Three studies showed significantly higher abstinence rates in a physically active group versus a control group at end of treatment. One of these studies also showed a significant benefit for exercise versus control on abstinence at the three-month follow up and a benefit for exercise of borderline significance (p = 0.05) at the 12-month follow up. One study showed significantly higher abstinence rates for the exercise group versus a control group at the three-month follow up but not at the end of treatment or 12-month follow up. The other studies showed no significant effect for exercise on abstinence.
AUTHORS' CONCLUSIONS: Only one of the 15 trials offered evidence for exercise aiding smoking cessation at a 12-month follow up. All the other trials were too small to reliably exclude an effect of intervention, or included an exercise intervention which was insufficiently intense to achieve the desired level of exercise. Trials are needed with larger sample sizes, sufficiently intense interventions, equal contact control conditions, and measures of exercise adherence and change in physical activity in both exercise and comparison groups.
定期锻炼可能有助于人们通过缓解尼古丁戒断症状和烟瘾,以及帮助控制体重增加来戒烟。
确定单独的基于运动的干预措施,或与戒烟计划相结合的干预措施,是否比单独的戒烟干预措施更有效。
2011年7月,我们在Cochrane烟草成瘾小组专业注册库中检索了包含“运动”或“体育活动”的研究。我们还使用“运动”或“体育活动”以及“戒烟”等术语在MEDLINE、EMBASE、PsycINFO、学位论文摘要和护理学与健康领域数据库中进行了检索。
我们纳入了随机试验,这些试验比较了单独的运动计划,或作为戒烟计划辅助手段的运动计划与戒烟计划,招募吸烟者或近期戒烟者,且随访时间为六个月或更长时间。
我们提取了关于研究特征和吸烟结果的数据。由于研究存在差异,我们以叙述方式总结了结果,未进行荟萃分析。
我们确定了15项试验,其中7项试验每个治疗组的人数少于25人。这些试验在戒烟和运动计划的时间安排和强度方面各不相同。三项研究表明,在治疗结束时,运动组的戒断率显著高于对照组。其中一项研究还表明,在三个月的随访中,运动组与对照组相比,在戒断方面有显著益处,在12个月的随访中,运动组的益处具有临界显著性(p = 0.05)。一项研究表明,在三个月的随访中,运动组的戒断率显著高于对照组,但在治疗结束时或12个月的随访中并非如此。其他研究表明运动对戒断没有显著影响。
15项试验中只有一项在12个月的随访中提供了运动有助于戒烟的证据。所有其他试验规模太小,无法可靠地排除干预效果,或者所纳入的运动干预强度不足以达到预期的运动水平。需要进行样本量更大、干预强度足够、接触控制条件相同以及对运动依从性和运动组与对照组体育活动变化进行测量的试验。