Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan.
Infect Drug Resist. 2011;4:221-4. doi: 10.2147/IDR.S24269. Epub 2011 Dec 15.
A necrotic lung ball is a rare radiological feature that is sometimes seen in cases of pulmonary aspergillosis. This paper reports a rare occurrence of a necrotic lung ball in a young male caused by Candida and Streptococcus pneumoniae.
A 28-year-old male with pulmonary candidiasis was found to have a lung ball on computed tomography (CT) of the chest. The patient was treated with β-lactams and itraconazole and then fluconazole, which improved his condition (as found on a following chest CT scan) and serum β-D-glucan level. The necrotic lung ball was suspected to have been caused by coinfection with Candida and S. pneumoniae.
A necrotic lung ball can result from infection by Candida and/or S. pneumoniae, indicating that physicians should be aware that patients may still have a fungal infection of the lungs that could result in a lung ball, even when they do not have either Aspergillus antibodies or antigens.
肺坏疽球是一种罕见的影像学特征,有时可见于肺曲霉病。本文报告了一例由念珠菌和肺炎链球菌引起的年轻男性肺坏疽球的罕见病例。
一名 28 岁男性患有肺念珠菌病,胸部 CT 发现肺坏疽球。患者接受了β-内酰胺类和伊曲康唑治疗,然后改用氟康唑,这改善了他的病情(如后续胸部 CT 扫描所示)和血清β-D-葡聚糖水平。坏死性肺坏疽球疑为由念珠菌和肺炎链球菌合并感染引起。
肺坏疽球可由念珠菌和/或肺炎链球菌感染引起,这表明医生应注意到,即使患者既没有曲霉菌抗体也没有曲霉菌抗原,他们仍可能患有肺部真菌感染,这可能导致肺坏疽球。