Lee Sub, Cho Jun-Woo, Kwon Oh-Choon
Department of Thoracic and Cardiovascular Surgery, School of Medicine, Catholic University of Daegu, Korea.
Korean J Thorac Cardiovasc Surg. 2011 Feb;44(1):72-5. doi: 10.5090/kjtcs.2011.44.1.72. Epub 2011 Feb 12.
Aortic thrombi are important because it can cause the central and peripheral embolizations. Aortic thrombi can occur anywhere in the aorta but extremely rare in ascending aorta without atherosclerosis, aneurysm, cardiosurgical or traumatic state. Systemic sclerosis (SSc) is an autoimmune disorder of connective tissue and it can involve multisystem. Enhanced coagulation pathways, decreased fibrinolysis, and endothelial dysfunction probably contribute to vascular events in SSc. We report a case of a highly mobile thrombus in the ascending aorta, presented as an acute embolic stroke in the patient with systemic sclerosis. Surgical removal was performed to prevent recurrent embolic events.
主动脉血栓很重要,因为它可导致中枢和外周栓塞。主动脉血栓可发生于主动脉的任何部位,但在无动脉粥样硬化、动脉瘤、心脏手术或创伤状态的升主动脉中极为罕见。系统性硬化症(SSc)是一种结缔组织自身免疫性疾病,可累及多个系统。凝血途径增强、纤维蛋白溶解减少以及内皮功能障碍可能导致系统性硬化症中的血管事件。我们报告一例升主动脉高度移动性血栓的病例,该病例在系统性硬化症患者中表现为急性栓塞性中风。进行了手术切除以预防复发性栓塞事件。