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升主动脉非瘤性非粥样硬化性大血栓栓子:病例报告。

Large mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta: a case report.

机构信息

Department of Cardiovascular Surgery, the First Affiliated Hospital, School of Medicine, Zhejiang University, 79# Qingchun Road, Hangzhou, Zhejiang, 310003, China.

School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.

出版信息

J Cardiothorac Surg. 2021 Jul 23;16(1):200. doi: 10.1186/s13019-021-01585-w.

DOI:10.1186/s13019-021-01585-w
PMID:34301282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8299447/
Abstract

BACKGROUND

The mural thrombus in the ascending aorta is rare, most of which are associated with aneurysm or atherosclerotic lesions, with high risks of causing catastrophic thrombotic events. A mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta is exceptionally uncommon.

CASE PRESENTATION

We reported a large mural thrombus in normal ascending aorta of an asymptomatic patient. Preoperative imaging confirmed the presence of the sessile thrombus located at the left anterior wall of ascending aorta. Given that it had the potential to cause fatal thrombotic complications, surgical removal and segment of ascending aorta replacement were executed. The patient had an uneventful recovery and discharged 14 days after surgery.

CONCLUSIONS

Anticoagulant is the therapeutic cornerstone of ascending aortic thrombus, but surgery should be performed aggressively when the thrombus is large or floating to avoid severe embolic complications or recurrence.

摘要

背景

升主动脉壁血栓较为罕见,多数与动脉瘤或粥样硬化病变相关,有发生灾难性血栓事件的高风险。非动脉瘤性和非粥样硬化性升主动脉壁血栓极为罕见。

病例介绍

我们报告了一例无症状患者正常升主动脉内的巨大壁血栓。术前影像学检查证实了位于升主动左前壁的附壁血栓的存在。鉴于其有引发致命性血栓并发症的可能,我们实施了手术切除和升主动脉节段置换。患者术后恢复顺利,术后 14 天出院。

结论

抗凝是升主动脉血栓的治疗基石,但当血栓较大或漂浮时,应积极进行手术,以避免严重的栓塞并发症或复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/879c/8306277/53b2cee8dc1e/13019_2021_1585_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/879c/8306277/e2da2cfee560/13019_2021_1585_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/879c/8306277/53b2cee8dc1e/13019_2021_1585_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/879c/8306277/e2da2cfee560/13019_2021_1585_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/879c/8306277/53b2cee8dc1e/13019_2021_1585_Fig2_HTML.jpg

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Acute myocardial infarction caused by a floating thrombus in the ascending aorta: A role of CD34-positive endothelial cells.升主动脉浮动血栓导致的急性心肌梗死:CD34 阳性内皮细胞的作用。
J Cardiol Cases. 2013 May 23;8(2):e88-e90. doi: 10.1016/j.jccase.2013.04.003. eCollection 2013 Aug.
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Aortic Mural Thrombus in the Non-atherosclerotic Aorta of Patients with Multiple Hypercoagulable Factors.
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Front Cardiovasc Med. 2023 Feb 24;10:1091303. doi: 10.3389/fcvm.2023.1091303. eCollection 2023.
具有多种高凝因素患者的非动脉粥样硬化性主动脉壁内血栓形成
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