Ivanković Mira, Bogoje-Raspopović Andrijana, Drobac Marina, Mamić-Martinović Drazana, Vodopić Maro
Department of Neurology, Dubrovnik General Hospital, Croatia.
Acta Clin Croat. 2011 Jun;50(2):253-5.
Benign angiopathy of the central nervous system is a subset of primary angiitis of the central nervous system characterized by "benign" course. It means that changes of cerebral vessels are reversible after treatment with corticosteroids and calcium channel blockers, so these abnormalities are believed to reflect vasospasm rather than true vasculitis. The diagnosis is made on the basis of clinical presentation, brain magnetic resonance imaging and cerebral angiography. We present a young man with acute onset of headache and neurologic impairment secondary to ischemic stroke with intracerebral and subarachnoid hemorrhage. Cerebral angiography showed characteristic findings of diffuse vasculitis but good response to treatment with corticosteroids and calcium channel blockers distinguish this benign angiopathy from the more aggressive form of the central nervous system vasculitis.
中枢神经系统良性血管病是中枢神经系统原发性血管炎的一个子集，其特征为病程“良性”。这意味着在用皮质类固醇和钙通道阻滞剂治疗后脑血管变化是可逆的，因此这些异常被认为反映的是血管痉挛而非真正的血管炎。诊断基于临床表现、脑磁共振成像和脑血管造影。我们报告一名年轻男性，因缺血性卒中继发脑内和蛛网膜下腔出血而急性起病，出现头痛和神经功能损害。脑血管造影显示弥漫性血管炎的特征性表现，但对皮质类固醇和钙通道阻滞剂治疗的良好反应将这种良性血管病与更具侵袭性的中枢神经系统血管炎形式区分开来。
