Sánchez Melissa D, Goldschmidt Michael H, Mauldin Elizabeth A
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA 19104, USA.
Vet Dermatol. 2012 Apr;23(2):171-3, e35. doi: 10.1111/j.1365-3164.2011.01031.x. Epub 2012 Jan 20.
Cats with feline herpesvirus (FeHV-1)-associated dermatitis typically present with ulcerative lesions on the rostral muzzle and nasal planum. This report describes FeHV-1 dermatitis in the flank region, in the absence of facial lesions.
HYPOTHESIS/OBJECTIVES: Clinicians should be aware of this unusual manifestation of FeHV-1 dermatitis to prevent potential misdiagnosis.
A 12-year-old male castrated Bengal cat and a 3-year-old male castrated Siamese cat with plaques and ulcers in the flank region are described.
Formalin-fixed biopsy samples were obtained from lesional skin. Histopathology and FeHV-1 immunohistochemistry were performed.
Each sample had epidermal and follicular necrosis with a dense dermal infiltrate of eosinophils. Few to moderate numbers of intranuclear inclusion bodies were present in keratinocytes. The presence of FeHV-1 in the lesions was confirmed with immunohistochemistry.
Feline herpesvirus-associated dermatitis should not be ruled out based on the location of the lesion, because a correct diagnosis is imperative for proper treatment. Future studies to assess the cause of lesions at this unusual site are warranted.
感染猫疱疹病毒1型（FeHV-1）的猫通常在吻部前端和鼻平面出现溃疡性病变。本报告描述了在无面部病变情况下，发生于胁腹区域的FeHV-1性皮炎。
假设/目的：临床医生应知晓FeHV-1性皮炎的这种不寻常表现，以防止潜在的误诊。
描述了一只12岁去势孟加拉雄猫和一只3岁去势暹罗雄猫，它们胁腹区域有斑块和溃疡。
从病变皮肤获取福尔马林固定的活检样本。进行组织病理学检查和FeHV-1免疫组化。
每个样本均有表皮和毛囊坏死，真皮有密集的嗜酸性粒细胞浸润。角质形成细胞中存在少量至中等数量的核内包涵体。免疫组化证实病变中存在FeHV-1。
不应仅根据病变部位排除猫疱疹病毒相关性皮炎，因为正确诊断对恰当治疗至关重要。有必要开展进一步研究以评估该不寻常部位病变的病因。
