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肺移植术后中间支气管并发症的管理:一项回顾性研究。

The management of bronchus intermedius complications after lung transplantation: a retrospective study.

作者信息

Lari Shahrzad M, Gonin Francois, Colchen Arlette

机构信息

Lung Disease and Tuberculosis Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Cardiothorac Surg. 2012 Jan 20;7:8. doi: 10.1186/1749-8090-7-8.

Abstract

BACKGROUND

Airway complications following lung transplantation remain a significant cause of morbidity and mortality. The management of bronchial complications in Bronchus Intermedius (BI) is challenging due to the location of right upper bronchus. The aim of this study was to analyze the results of BI Montgomery T-tube stent in a consecutive patients with lung transplantations.

METHODS

Between January 2007 and December 2010, 132 lung transplantations were performed at Foch Hospital, Suresnes, France. All the patients who had BI Montgomery T-tube after lung transplantation were included in this retrospective study. The demographic and interventional data and also complications were recorded.

RESULTS

Out of 132 lung transplant recipients, 12 patients (9 male and 3 female) were entered into this study. The indications for lung transplantation were: cystic fibrosis 8 (67%), emphysema 3 (25%), and idiopathic pulmonary fibrosis 1 (8%). Most of the patients (83%) had bilateral lung transplantation. The mean interval between lung transplantation and interventional bronchoscopy was 11.5 ± 9.8 (SD) months. There was bronchial stenosis at the level of BI in 7 patients (58.3%). The Montgomery T-tube number 10 was used in 9 patients (75%). There was statistically significant difference in Forced Expiratory Volume in one second (FEV1) before and after stent placement (p = 0.01). The most common complication after stent placement was migration (33%).

CONCLUSION

BI complications after lung transplantation are still a significant problem. Stenosis or malacia following lung transplantation could be well managed with modified Montgomery T-tube.

摘要

背景

肺移植后的气道并发症仍然是发病和死亡的重要原因。由于右上支气管的位置,中间支气管(BI)的支气管并发症管理具有挑战性。本研究的目的是分析连续肺移植患者中BI蒙哥马利T型管支架的治疗结果。

方法

2007年1月至2010年12月,法国叙雷讷市福煦医院进行了132例肺移植手术。本回顾性研究纳入了所有肺移植后放置BI蒙哥马利T型管的患者。记录人口统计学和干预数据以及并发症情况。

结果

132例肺移植受者中,12例患者(9例男性和3例女性)纳入本研究。肺移植的适应证为:囊性纤维化8例(67%),肺气肿3例(25%),特发性肺纤维化1例(8%)。大多数患者(83%)接受了双侧肺移植。肺移植与介入性支气管镜检查之间的平均间隔时间为11.5±9.8(标准差)个月。7例患者(58.3%)在BI水平存在支气管狭窄。9例患者(75%)使用了1型号的蒙哥马利T型管。支架置入前后一秒用力呼气量(FEV1)有统计学显著差异(p = 0.01)。支架置入后最常见的并发症是移位(33%)。

结论

肺移植后的BI并发症仍然是一个重大问题。肺移植后的狭窄或软化可以通过改良的蒙哥马利T型管得到良好管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf52/3275502/451db8855626/1749-8090-7-8-1.jpg

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