Nazzal Mahmoud E, Saadah Mohammed A, Trebinjac Suad M, Al-Awadi Omar A, Al-Shamsi Khalid A
Physical Medicine and Rehabilitation Department, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Neurosciences (Riyadh). 2006 Jan;11(1):15-20.
The incidence of stroke and the demand for rehabilitation services continues to increase. Risk factors may act as stroke outcome predictors and hence determine the type and intensity of rehabilitation. Our aim is to investigate stroke outcome predictors that will define groups with maximal or minimal benefit from rehabilitation after stroke.
Our longitudinal prospective study included 111 ischemic stroke patients, admitted consecutively to the Rehabilitation Department, Hamad Medical Corporation, Qatar, during 2000-2001. We analyzed the influence of modifiable risk factors: diabetes mellitus (DM), hypertension (HTN), ischemic heart disease (IHD) and non-modifiable factors: age, gender, race and side of lesion on stroke outcome. All patients received regular rehabilitation and underwent an evaluation on admission and discharge, using the Modified Barthel Index.
Statistical analysis demonstrated that the group of patients with IHD showed greatest improvement after 3 months of rehabilitation. The group without co-morbidities followed this, and then the HTN, DM, combined DM and HTN and combined HTN and IHD groups. The group that suffered from combined DM, HTN, and IHD did not show improvement. Non-modifiable risk factors showed no significant differences. However, younger patients showed a tendency for better improvement.
Those patients with modifiable risk factors had significant impact on rehabilitation outcome (p-value = 0.009). Those with one or 2 co-morbidities had the highest score of improvement after rehabilitation while the group of patients with more than 2 co-morbidities did not show improvement. However, non-modifiable risk factors did not play a significant role in stroke outcome.
中风的发病率以及对康复服务的需求持续上升。风险因素可能作为中风预后的预测指标,从而决定康复的类型和强度。我们的目的是研究中风预后预测指标,这些指标将确定中风后从康复中获益最大或最小的群体。
我们的纵向前瞻性研究纳入了2000年至2001年期间连续入住卡塔尔哈马德医疗公司康复科的111例缺血性中风患者。我们分析了可改变的风险因素:糖尿病(DM)、高血压(HTN)、缺血性心脏病(IHD)以及不可改变的因素:年龄、性别、种族和病变部位对中风预后的影响。所有患者均接受常规康复治疗,并在入院和出院时使用改良巴氏指数进行评估。
统计分析表明,患有IHD的患者组在康复3个月后改善最大。无合并症的患者组次之,然后是HTN组、DM组、DM和HTN合并组以及HTN和IHD合并组。患有DM、HTN和IHD合并症的患者组没有改善。不可改变的风险因素没有显著差异。然而,年轻患者有更好改善的趋势。
那些具有可改变风险因素的患者对康复结局有显著影响(p值 = 0.009)。那些有1种或2种合并症的患者在康复后改善得分最高,而有超过2种合并症的患者组没有改善。然而,不可改变的风险因素在中风预后中没有发挥显著作用。