Dept of Pneumology, Medical School Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Eur Respir J. 2012 Jul;40(1):143-51. doi: 10.1183/09031936.00204611. Epub 2012 Jan 20.
4,444 new cases of tuberculosis (TB) were reported in Germany in 2009; of those, the proportion of multidrug-resistant (MDR)-TB cases increased to 2.1% (63 cases). On the basis of the therapy guidelines of the German Central Committee against Tuberculosis and the new World Health Organization guidelines, this study estimates the mean direct outpatient and combined in- and outpatient costs of TB, together with other attributable costs of the disease on the basis of the most recent German official health statistics and scientific literature. According to this, the mean outpatient costs (rounded) per case were €1,197 (adults) and €1,006 (children) for standard therapy, but €36,543 for treatment of MDR-TB. The mean combined in-patient/outpatient costs were €7,364 (adults) and €7,300 (children), respectively; the combined costs for treatment of MDR-TB amounted to €52,259. Including MDR-TB cases the mean costs of treatment per TB case were €7,931. These are joined by the mean costs due to loss of productivity (€2,313), costs per case for rehabilitation (€74) and contact tracing (€922), adding up to €11,240. When considering the probability of increasing numbers of MDR-TB cases in the near future, TB is still a disease of significant economic impact in Germany.
2009 年德国报告了 4444 例新的肺结核（TB）病例；其中，耐多药（MDR）-TB 病例的比例增加到 2.1%（63 例）。基于德国中央结核病防治委员会和新的世界卫生组织指南的治疗指南，本研究根据最新的德国官方卫生统计数据和科学文献，估计了 TB 的平均直接门诊和联合门诊和住院费用，以及该疾病的其他相关费用。根据这一估计，标准治疗的平均门诊费用（四舍五入）为每例 1197 欧元（成人）和 1006 欧元（儿童），但 MDR-TB 的治疗费用为 36543 欧元。平均联合门诊和住院费用分别为 7364 欧元（成人）和 7300 欧元（儿童）；MDR-TB 的联合治疗费用为 52259 欧元。包括 MDR-TB 病例在内，每例 TB 的治疗平均费用为 7931 欧元。这些费用加上因生产力损失而产生的平均费用（2313 欧元）、每例康复费用（74 欧元）和接触者追踪费用（922 欧元），总计为 11240 欧元。考虑到未来 MDR-TB 病例数量可能增加，TB 在德国仍然是一种具有重大经济影响的疾病。
