Weihmiller Sarah N, Monuteaux Michael C, Bachur Richard G
Division of Emergency Medicine, Children's Hospital, Boston, MA, USA.
Pediatr Emerg Care. 2012 Feb;28(2):136-40. doi: 10.1097/PEC.0b013e3182442db1.
Intussusception is the most common cause of intestinal obstruction in infants and children. To date, no study has evaluated the ability of physicians to predict the likelihood of intussusception.
This study aimed to determine the ability of pediatric physicians to predict intussusception in patients being evaluated for intussusception and to investigate whether certain clinical findings correlate with physicians' risk assessment.
A prospective cohort study of children aged 1 month to 6 years who presented with possible intussusception. The predicted likelihood of intussusception was recorded by physicians before knowledge of imaging results or final diagnosis. We defined a physician's prediction as high versus low risk based on a threshold prediction of 25% likelihood.
A total of 308 patients were studied including 38 (12.3%) with intussusception. Physicians' prediction was positively associated with the risk of intussusception (test for linear trend: odds ratio [OR], 2.1; 95% confidence interval [CI], 1.6-2.7; P < 0.001). Among patients considered high risk, the rate of intussusception was 36% (95% CI, 25%-49%) compared with 6% for those judged to be low risk (95% CI, 4%-10%). Using a threshold of 25% likelihood, successful prediction of high versus low risk occurred in 82% (95% CI, 77%-86%). Clinical predictors associated with assigning a designation of higher risk of intussusception included lethargy at home (OR, 2.7; 95% CI, 1.4-5.5) and bloody stool (OR, 2.5; 95% CI, 1.0-5.9).
Pediatric physicians can accurately predict the likelihood of intussusception. This ability to properly judge the risk of intussusception can be incorporated into management strategies.
肠套叠是婴幼儿肠梗阻最常见的病因。迄今为止,尚无研究评估医生预测肠套叠可能性的能力。
本研究旨在确定儿科医生预测接受肠套叠评估患者发生肠套叠的能力,并调查某些临床发现是否与医生的风险评估相关。
对1个月至6岁出现可能肠套叠症状的儿童进行前瞻性队列研究。在知晓影像学结果或最终诊断之前,医生记录肠套叠的预测可能性。基于25%可能性的阈值预测,我们将医生的预测定义为高风险与低风险。
共研究了308例患者,其中38例(12.3%)患有肠套叠。医生的预测与肠套叠风险呈正相关(线性趋势检验:比值比[OR],2.1;95%置信区间[CI],1.6 - 2.7;P < 0.001)。在被认为高风险的患者中,肠套叠发生率为36%(95% CI,25% - 49%),而被判定为低风险的患者发生率为6%(95% CI,4% - 10%)。使用25%可能性的阈值,高风险与低风险的成功预测率为82%(95% CI,77% - 86%)。与判定为肠套叠高风险相关的临床预测因素包括在家中嗜睡(OR,2.7;95% CI,1.4 - 5.5)和血便(OR,2.5;95% CI,1.0 - 5.9)。
儿科医生能够准确预测肠套叠的可能性。这种正确判断肠套叠风险的能力可纳入管理策略中。