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香港首个全人群乳腺癌特定登记处的早期数据。

Early data from the first population-wide breast cancer-specific registry in Hong Kong.

机构信息

Hong Kong Breast Cancer Foundation, 22/F, Jupiter Tower, No. 9, Jupiter Street North Point, Hong Kong, China.

出版信息

World J Surg. 2012 Apr;36(4):723-9. doi: 10.1007/s00268-012-1426-2.

Abstract

BACKGROUND

Current measures for breast cancer prevention and options for treatment adopted in Hong Kong are mainly based on research data and clinical evidence from overseas. It is essential to establish a cancer-specific registry to monitor the status of breast cancer in Hong Kong.

OBJECTIVES

We summarized the current status of breast cancer in Hong Kong based on the data collected from Hong Kong Breast Cancer Registry (HKBCR).

METHODS

Prevalent and newly diagnosed breast cancers (including in situ and invasive breast cancers) were registered in the HKBCR. Information on patient demographics, risk factors, medical information, and survival were analyzed and reported in this study.

RESULTS

Data of 2,330 breast cancer patients were analyzed. We observed an earlier median age at diagnosis in Hong Kong than those reported in other countries. Distribution of cancer stage was: stage 0 (11.4%), stage I (31.4%), stage II (41%), stage III (12.5%), stage IV (0.8%), and unclassified (2.9%). The percentages of patients who received surgery, chemotherapy, radiation therapy, and endocrine therapy were 98.7, 67.9, 64.8, and 64.1%, respectively. At a median follow-up of 1.2 years, locoregional recurrence was recorded at 2%, distant recurrence at 2.8%, and breast-cancer-related mortality at 0.3%.

CONCLUSIONS

The HKBCR serves as a surveillance program to monitor disease and treatment patterns. It is pivotal to support research for more effective breast cancer prevention and treatment strategies in Hong Kong.

摘要

背景

香港目前的乳腺癌预防措施和治疗选择主要基于海外的研究数据和临床证据。建立一个专门的癌症登记处来监测香港的乳腺癌状况至关重要。

目的

我们根据香港乳腺癌登记处(HKBCR)收集的数据,总结了香港乳腺癌的现状。

方法

HKBCR 登记了现患和新诊断的乳腺癌(包括原位和浸润性乳腺癌)。本研究分析并报告了患者人口统计学、风险因素、医疗信息和生存情况等信息。

结果

对 2330 例乳腺癌患者的数据进行了分析。我们观察到香港的诊断中位年龄早于其他国家报告的年龄。癌症分期分布为:0 期(11.4%)、I 期(31.4%)、II 期(41%)、III 期(12.5%)、IV 期(0.8%)和未分类(2.9%)。接受手术、化疗、放疗和内分泌治疗的患者比例分别为 98.7%、67.9%、64.8%和 64.1%。在中位随访 1.2 年时,记录到局部区域复发率为 2%、远处复发率为 2.8%和乳腺癌相关死亡率为 0.3%。

结论

HKBCR 作为监测疾病和治疗模式的监控计划。它对于支持香港开展更有效的乳腺癌预防和治疗策略的研究至关重要。

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