Centro Nacional de Investigaciones Metalúrgicas (CENIM-CSIC), Madrid, Spain.
J Mater Sci Mater Med. 2012 Mar;23(3):657-66. doi: 10.1007/s10856-012-4549-y. Epub 2012 Jan 22.
This study reports on the biocompatibility of 316 LVM steel blasted with small and rounded ZrO(2) particles or larger and angular shaped Al(2)O(3) particles. The effect of blasting on the in vitro corrosion behavior and the associated ion release is also considered. Surface of Al(2)O(3) blasted samples was rougher than that of ZrO(2) blasted samples, which was also manifested by a higher surface area. Compared to the polished alloy, blasted steels exhibited a lower corrosion resistance at the earlier stages of immersion, particularly when using Al(2)O(3) particles. With increasing immersion time, blasted samples experienced an improvement of the corrosion resistance, achieving impedance values typical of passive alloys. Blasting of the alloy led to an increase in Fe release and the leaching of Ni, Mn, Cr and Mo. On all surfaces, ion release is higher during the first 24 h exposure and tends to decrease during the subsequent exposure time. Despite the lower corrosion resistance and higher amount of ions released, blasted alloys exhibit a good biocompatibility, as demonstrated by culturing osteoblastic cells that attached and grew on the surfaces.
本研究报告了经小而圆的 ZrO(2)颗粒或大而角状的 Al(2)O(3)颗粒喷射处理后的 316LVM 钢的生物相容性。还考虑了喷射处理对体外腐蚀行为和相关离子释放的影响。与 ZrO(2)喷射处理的样品相比,Al(2)O(3)喷射处理的样品表面更粗糙,这也表现为更高的表面积。与抛光合金相比,喷射处理的钢在浸泡的早期阶段表现出较低的耐腐蚀性,特别是使用 Al(2)O(3)颗粒时。随着浸泡时间的增加,喷射处理的样品的耐腐蚀性得到改善,达到了典型的钝化合金的阻抗值。合金的喷射处理导致 Fe 的释放增加和 Ni、Mn、Cr 和 Mo 的浸出。在所有表面上,离子释放在前 24 小时暴露期间较高,并在随后的暴露时间内趋于降低。尽管耐腐蚀性较低且释放的离子量较高,但喷射处理的合金表现出良好的生物相容性,成骨细胞附着和生长在表面上证明了这一点。