Cosgrove M, Pople S, Wallace S J
University Hospital of Wales, Heath Park, Cardiff.
Dev Med Child Neurol. 1990 Sep;32(9):796-9. doi: 10.1111/j.1469-8749.1990.tb08484.x.
The usefulness of rapid anti-epileptic drug assay in a paediatric neurology clinic was assessed. Compared with a method in which results were not available for seven to 10 days, there was an increased likelihood that levels would be within the target range, particularly for carbamazepine. Increased parental discussion, and therefore involvement with dosage, was possible. Management of children receiving phenytoin was more efficient and non-compliance could be dealt with immediately. When anti-epileptic drug levels are measured, rapid assay, with results available while the patient is still in the clinic, should be a standard facility.
评估了快速抗癫痫药物检测在儿科神经科门诊的实用性。与一种结果需要7至10天才能获得的方法相比,药物水平处于目标范围内的可能性增加,尤其是卡马西平。增加了家长讨论,因此家长对剂量的参与度也增加了。接受苯妥英治疗的儿童的管理更有效,不依从性问题可以立即得到处理。在检测抗癫痫药物水平时,快速检测(在患者仍在门诊时即可获得结果)应成为一项标准设施。