Department of Neurosurgery, Carle Foundation Hospital, University of Illinois College of Medicine at Urbana/Champaign, Illinois, USA.
Neurosurgery. 2012 Jun;70(6):1581-8; discussion 1588. doi: 10.1227/NEU.0b013e31824c00f4.
Posterior cerebral artery (PCA) aneurysms are relatively rare, making up 1% to 2% of all intracranial aneurysms. To date, most clinical series are heterogeneous in nature, with few reports of isolated PCA dissecting aneurysms. Their clinical presentation can vary greatly, and the potential for long-term sequelae during or after treatment remains relatively high.
To report our recent experience in 9 consecutive patients with PCA dissecting aneurysms with a discussion of the unique clinical challenges of their evaluation and treatment.
We conducted a retrospective review of 9 consecutive patients with PCA dissecting aneurysms from November 2003 to February 2010. Their hospital charts and follow-up records were reviewed and summarized.
: We identified 6 male and 3 female patients ranging in age from 7 months to 69 years (median age, 53 years). None had any associated trauma. Four patients presented with subarachnoid hemorrhage. Three presented with intraventricular and intracerebral hemorrhage. The remaining 2 presented with headache and acute onset of right-sided numbness, respectively. Four underwent endovascular embolization; 2 underwent surgical clipping; and the remaining 3 were managed medically and followed up conservatively. The dissecting aneurysms involved P1 (n = 2), P1-2 junction (n = 1), P2 (n = 4), and P2-3 junction (n = 1). At a mean follow-up of 3 months, 6 patients had excellent functional outcome with modified Rankin Scale score of 0 or 1. The remaining 3 patients who presented in deep coma did poorly (1 died and 2 had severe disabilities).
PCA dissecting aneurysms pose a unique challenge and have many unresolved issues regarding treatment modalities.
大脑后动脉(PCA)动脉瘤相对罕见,占所有颅内动脉瘤的 1%至 2%。迄今为止,大多数临床系列本质上是异质的,孤立的 PCA 夹层动脉瘤的报道很少。其临床表现差异很大,在治疗过程中或之后发生长期后遗症的可能性仍然相对较高。
报告我们最近治疗 9 例 PCA 夹层动脉瘤患者的经验,并讨论其评估和治疗的独特临床挑战。
我们回顾性分析了 2003 年 11 月至 2010 年 2 月期间 9 例连续的 PCA 夹层动脉瘤患者。回顾并总结了他们的病历和随访记录。
我们共发现 6 例男性和 3 例女性患者,年龄从 7 个月至 69 岁不等(中位数年龄为 53 岁)。均无任何相关外伤。4 例患者表现为蛛网膜下腔出血。3 例患者表现为脑室和脑内出血。其余 2 例分别表现为头痛和右侧麻木急性发作。4 例行血管内栓塞治疗;2 例行手术夹闭;其余 3 例采用药物治疗并保守随访。夹层动脉瘤分别位于 P1(n=2)、P1-2 交界处(n=1)、P2(n=4)和 P2-3 交界处(n=1)。平均随访 3 个月时,6 例患者改良Rankin 量表评分 0 或 1,功能预后良好。3 例深昏迷患者预后较差(1 例死亡,2 例严重残疾)。
PCA 夹层动脉瘤治疗具有独特的挑战性,并且在治疗方式方面存在许多尚未解决的问题。