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大脑后动脉脑动脉瘤的血管内治疗

Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery.

作者信息

Li Xin-Yu, Li Cong-Hui, Wang Ji-Wei, Liu Jian-Feng, Li Hui, Gao Bu-Lang

机构信息

Department of Neurosurgery, The First Hospital, Hebei Medical University, Shijiazhuang, China.

出版信息

Front Neurol. 2021 Oct 21;12:700516. doi: 10.3389/fneur.2021.700516. eCollection 2021.

Abstract

To investigate the safety and efficacy of endovascular embolization of cerebral aneurysms at the P1-P3 segments of the posterior cerebral artery (PCA). Seventy-seven patients with 77 PCA aneurysms who were treated with endovascular embolization were enrolled, including 35 (45.5%) patients with ruptured aneurysms and 42 (54.5%) with unruptured ones. The pretreatment clinical data and aneurysm occlusion status after treatment and at follow-up were analyzed. All patients were successfully treated endovascularly, including coiling alone in 10 (13.0%) patients, stent-assisted coiling in 18 (23.4%), parent artery occlusion in 25 (32.5%), and pipeline embolization device (PED) in 24 (31.2%). Complete occlusion was achieved in 48 (62.3%) aneurysms, residual neck in 4 (5.2%), and residual aneurysm in the other 25 (32.5%) at the end of embolization. Periprocedural complications occurred in eight patients, including acute thrombosis in seven (9.1%) and intraprocedural subarachnoid hemorrhage in one (1.3%), with the total complication rate of 10.4%. Follow-up was performed in 60 patients (77.9%) for 42 ± 11 months; the mRS score was 0-2 in 55 (91.7%) patients, three in four patients (6.7%), and six in one patient (1.7%). Fifty-three (88.3%) patients (53 aneurysms) had stable or complete occlusion, and seven (11.7%) patients had aneurysm recurrence or residual aneurysm. Among 19 patients treated with PED at follow-up, 15 aneurysms (78.9%) proceeded to complete occlusion while four (21.1%) aneurysms showed residual aneurysm. Endovascular embolization remains a good choice of treatment with high safety and efficacy for posterior cerebral artery aneurysms.

摘要

探讨大脑后动脉(PCA)P1 - P3段脑动脉瘤血管内栓塞术的安全性和有效性。纳入77例接受血管内栓塞治疗的77个PCA动脉瘤患者,其中35例(45.5%)为破裂动脉瘤患者,42例(54.5%)为未破裂动脉瘤患者。分析治疗前临床资料以及治疗后和随访时的动脉瘤闭塞情况。所有患者均成功接受血管内治疗,其中单纯弹簧圈栓塞10例(13.0%),支架辅助弹簧圈栓塞18例(23.4%),载瘤动脉闭塞25例(32.5%),密网支架(PED)置入24例(31.2%)。栓塞结束时,48个(62.3%)动脉瘤实现完全闭塞,4个(5.2%)有残余瘤颈,另外25个(32.5%)有残余动脉瘤。围手术期并发症发生在8例患者中,包括7例(9.1%)急性血栓形成和1例(1.3%)术中蛛网膜下腔出血,总并发症发生率为10.4%。60例患者(77.9%)进行了42±11个月的随访;改良Rankin量表(mRS)评分0 - 2分的患者有55例(91.7%),3分的有4例(6.7%),6分的有1例(1.7%)。53例(88.3%)患者(53个动脉瘤)实现稳定或完全闭塞,7例(11.7%)患者动脉瘤复发或有残余动脉瘤。随访时接受PED治疗的19例患者中,15个(78.9%)动脉瘤实现完全闭塞,4个(21.1%)动脉瘤有残余动脉瘤。血管内栓塞术仍是治疗大脑后动脉动脉瘤的一种安全性和有效性高的良好选择。

相似文献

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Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery.大脑后动脉脑动脉瘤的血管内治疗
Front Neurol. 2021 Oct 21;12:700516. doi: 10.3389/fneur.2021.700516. eCollection 2021.

本文引用的文献

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Outcomes of multidisciplinary treatment for posterior cerebral artery aneurysms.大脑后动脉动脉瘤的多学科治疗结果
Clin Neurol Neurosurg. 2013 Oct;115(10):2062-8. doi: 10.1016/j.clineuro.2013.07.004. Epub 2013 Jul 30.

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