卡介苗接种后发生的骨髓炎。

Osteomyelitis following Bacille Calmette-Guerin vaccination.

作者信息

Al-Jassir Fawzi F, Aldeeri Riyadh A, Alsiddiky Abdul-Monem M, Zamzam Mohamed M

机构信息

Department of Orthopedics, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

出版信息

Saudi Med J. 2012 Jan;33(1):87-90.

PMID:22273655

Abstract

Secondary complications after Bacille Calmette-Guerin (BCG) vaccination are unusual. We describe 3 immunocompetent children who developed osteomyelitis after BCG vaccination. The course of the disease is not dramatic, but marked changes are frequently visible in plain radiograph and MRI. The real-time polymerase chain reaction has an essential role to confirm the diagnosis of BCG osteomyelitis. With proper surgical intervention and chemotherapy, the prognosis is usually good.

摘要

卡介苗（BCG）接种后的继发性并发症并不常见。我们描述了3名免疫功能正常的儿童，他们在接种卡介苗后发生了骨髓炎。疾病过程并不严重，但在X线平片和磁共振成像（MRI）上经常可见明显变化。实时聚合酶链反应在确诊卡介苗骨髓炎方面起着至关重要的作用。通过适当的手术干预和化疗，预后通常良好。