一种无标签凝血酶结合适体作为探针，通过共振瑞利散射法实现对铅（II）离子的高灵敏和选择性检测。
A label-free thrombin binding aptamer as a probe for highly sensitive and selective detection of lead(II) ions by a resonance Rayleigh scattering method.
机构信息
Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China.
出版信息
Analyst. 2012 Mar 7;137(5):1097-9. doi: 10.1039/c2an15980e. Epub 2012 Jan 25.
PMID:22273760
Abstract
The binding of lead(II) ions with unusually high affinity to a thrombin binding aptamer resulted in an enhancement of resonance Rayleigh scattering (RRS). A simple, sensitive, and selective assay for the direct determination of trace amounts of Pb(2+) on the basis of RRS has been proposed.
摘要
与凝血酶结合适体具有异常高亲和力的铅（II）离子结合导致共振瑞利散射（RRS）增强。基于 RRS，提出了一种简单、灵敏、选择性的测定痕量 Pb(2+)的直接测定方法。
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