Headache Group, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Curr Pain Headache Rep. 2012 Apr;16(2):162-9. doi: 10.1007/s11916-012-0248-0.
Post-traumatic headache (PTH) is a common and well-recognized entity. Tension-type headache and migraine are the commonest phenotypes that can result from head trauma, while the onset of cluster headache (CH) in close temporal relation to a head trauma has only been described in rare cases. Nevertheless, CH patients seem to incur more frequent traumatic head injuries during their lifetimes when compared to migraine controls and the general population. The basis of this association remains unclear, since only a limited number of methodologically robust studies have examined it. However, three main hypotheses can be proposed to explain this association: head trauma is the direct cause of CH; head trauma is a risk factor for the future development of CH; and head trauma is a consequence of a CH trait. A better understanding of the association between head trauma and CH may provide important insights into both the pathophysiology of CH and the mechanisms by which traumatic head injury predisposes patients to developing headaches.
创伤后头痛（PTH）是一种常见且公认的病症。紧张型头痛和偏头痛是最常见的头痛类型，可能由头部创伤引起，而在头部创伤后紧接出现丛集性头痛（CH）的情况则很少见。然而，与偏头痛对照组和一般人群相比，CH 患者在其一生中似乎更容易遭受创伤性头部损伤。这种关联的基础尚不清楚，因为只有少数方法学上可靠的研究对其进行了研究。然而，可以提出三个主要假设来解释这种关联：头部创伤是 CH 的直接原因；头部创伤是 CH 未来发展的危险因素；头部创伤是 CH 特征的后果。更好地了解头部创伤与 CH 之间的关联可能会为 CH 的病理生理学以及创伤性头部损伤使患者易患头痛的机制提供重要的见解。
