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Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres.
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Linking functional decline of telomeres, mitochondria and stem cells during ageing.
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Hypoxia mediates low cell-cycle activity and increases the proportion of long-term-reconstituting hematopoietic stem cells during in vitro culture.
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Senescence in tumours: evidence from mice and humans.
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PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.
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