Doshi Bhavana R, Mahajan Sunanda, Kharkar Vidya, Khopkar Uday S
Department of Dermatology, Seth GS Medical College and KEM Hospital, Mumbai, India.
Pediatr Dermatol. 2013 Jul-Aug;30(4):e48-51. doi: 10.1111/j.1525-1470.2011.01666.x. Epub 2012 Jan 26.
Two infants presented with multiple asymptomatic papules and geographic and annular plaques over the extensor aspect of the upper and lower extremities and trunk. Skin biopsy of both lesions showed plugged and hyperplastic dilated acrosryingia and deep dermal ducts, along with granulomatous inflammatory reaction. These lesions showed self-healing with complete resolution. A previous report described similar clinical and histopathologic features and labeled it giant centrifugal miliaria profunda. Because of the large granulomatous plaques and deep infiltrate, we propose that it was a granulomatous variant of giant centrifugal miliaria profunda. We report these cases for their rarity and self-healing nature.
两名婴儿的上肢、下肢及躯干伸侧出现多个无症状丘疹以及地图状和环状斑块。对两处皮损进行皮肤活检，结果显示顶泌汗腺导管堵塞且增生性扩张，真皮深层导管亦如此，同时伴有肉芽肿性炎症反应。这些皮损可自行愈合且完全消退。此前有报告描述了类似的临床和组织病理学特征，并将其命名为巨大离心性深部粟丘疹。鉴于出现了较大的肉芽肿性斑块及深部浸润，我们认为这是巨大离心性深部粟丘疹的肉芽肿性变异型。我们报告这些病例是因其罕见性及自行愈合的特性。
