Goldstein Stuart L
Department of Pediatrics, University of Cincinnati College of Medicine and the Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45206, USA.
Semin Dial. 2012 Mar-Apr;25(2):165-70. doi: 10.1111/j.1525-139X.2011.01028.x. Epub 2012 Jan 25.
The provision of therapeutic apheresis to children is a technically challenging procedure, requiring trained personnel and an understanding of the disease processes that leads to the need for apheresis. Most apheresis protocols are derived from studies in adult patients, even though most studies are of limited sample size. The focus of this review is to highlight the disease processes commonly treated with therapeutic apheresis in children, and to address the technical considerations pertinent to the provision of safe and effective apheresis in the pediatric setting.
为儿童提供治疗性血液成分单采是一项技术上具有挑战性的操作,需要训练有素的人员以及对导致需要进行血液成分单采的疾病过程有所了解。尽管大多数研究的样本量有限,但大多数血液成分单采方案都源自对成年患者的研究。本综述的重点是强调儿童中通常采用治疗性血液成分单采治疗的疾病过程,并探讨在儿科环境中提供安全有效的血液成分单采相关的技术考量。