评估一种用于检测血清、全血、尿液和胃内容物中麦角酰二乙胺（LSD）的商用放射免疫分析试剂盒。
Evaluation of a commercial radioimmunoassay kit for the detection of lysergide (LSD) in serum, whole blood, urine and stomach contents.
作者信息
Altunkaya D, Smith R N
机构信息
Metropolitan Police Forensic Science Laboratory, London, U.K.
出版信息
Forensic Sci Int. 1990 Sep;47(2):113-21. doi: 10.1016/0379-0738(90)90205-d.
The Diagnostic Products Corporation Coat-A-Count radioimmunoassay kit for LSD in urine has been evaluated for use in forensic toxicology with a variety of sample types. The cut-offs (defined as the mean response of blank samples plus three standard deviation) for LSD in serum, haemolysed whole blood, urine and stomach contents were 0.06, 0.050-0.055, 0.18 and 0.18 ng/ml, respectively. Preliminary extraction of LSD from the samples is not usually necessary. The precision of the analysis and the recoveries from spiked samples were satisfactory. The cross-reactivities of 2-oxo-LSD, lysergic acid methyl propylamide, lysergic acid monoethylamide and nor-LSD were estimated to be 11,6,2 and 1% respectively relative to LSD (100%).
已对诊断产品公司的尿液中麦角酰二乙胺（LSD）Coat - A - Count放射免疫分析试剂盒进行了评估，以用于多种样本类型的法医毒理学检测。血清、溶血全血、尿液和胃内容物中LSD的临界值（定义为空白样本的平均响应值加上三个标准差）分别为0.06、0.050 - 0.055、0.18和0.18纳克/毫升。通常无需对样本进行LSD的初步提取。分析的精密度和加标样本的回收率令人满意。相对于LSD（100%），2 - 氧代 - LSD、麦角酰甲基丙基酰胺、麦角酰单乙酰胺和去甲LSD的交叉反应率估计分别为11%、6%、2%和1%。
Zotero 插件