Suppr超能文献

[肌萎缩侧索硬化症和帕金森病吞咽困难的评估与治疗]

[Evaluation and treatment of dysphagia in amyotrophic lateral sclerosis and Parkinson's disease].

作者信息

Yamamoto Toshiyuki

机构信息

Department of Neurology, National Center Hospital of Neurology and Psychiatry.

出版信息

Rinsho Shinkeigaku. 2011 Nov;51(11):1072-4. doi: 10.5692/clinicalneurol.51.1072.

Abstract

As both amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD) exhibit a variety of patterns of dysphagia, appropriate symptomatic treatment is provided after evaluation of swallowing function through videofluoroscopic examination of swallowing. In ALS, disease progression is rapid, therefore, respiratory function, swallowing function and nutritional status should be evaluated regularly. When the oral or pharyngeal stage of swallowing are affected early in dysphagia, adjusting swallowing volume and varying consistency can be beneficial in ALS. When all stages of swallowing are impaired in ALS, such complications as pneumonia, dehydration and malnutrition, are observed. In such patients, it is necessary to consider an alternative to oral dietary intake. In PD, dysphagia is not necessarily associated with severity of parkinsonism and can appear at any time during the course of the disease. Dysphagia in PD can occur at any stage of swallowing and frequently accompanies multiple abnormalities. In particular, aspiration is an important risk factor for pneumonia in PD. The effect of L-dopa treatment for dysphagia is often insufficient; however, this treatment remains the first choice because dysphagia is exacerbated during off state. Rehabilitation for dysphagia in PD has also some effect.

摘要

由于肌萎缩侧索硬化症(ALS)和帕金森病(PD)都表现出多种吞咽困难模式,因此在通过吞咽视频荧光检查评估吞咽功能后,会提供适当的对症治疗。在ALS中,疾病进展迅速,因此应定期评估呼吸功能、吞咽功能和营养状况。当吞咽困难早期影响到口腔或咽部阶段时,调整吞咽量和改变食物稠度对ALS可能有益。当ALS患者吞咽的所有阶段都受损时,会出现诸如肺炎、脱水和营养不良等并发症。对于这类患者,有必要考虑替代经口饮食摄入的方法。在PD中,吞咽困难不一定与帕金森病的严重程度相关,并且可能在疾病过程中的任何时候出现。PD患者的吞咽困难可发生在吞咽的任何阶段,并经常伴有多种异常。特别是误吸是PD患者发生肺炎的重要危险因素。左旋多巴治疗吞咽困难的效果往往不足;然而,这种治疗仍然是首选,因为在“关”期吞咽困难会加重。PD患者吞咽困难的康复治疗也有一定效果。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验