Breast Cancer Res. 2012 Jan 25;14(1):102. doi: 10.1186/bcr3081.
Few studies have investigated the association of non-dense area or fatty breasts in conjunction with breast density and breast cancer risk. Two articles in a recent issue of Breast Cancer Research investigate the role of absolute non-dense breast area measured on mammograms and find conflicting results: one article finds that non-dense breast area has a modest positive association with breast cancer risk, whereas the other finds that non-dense breast area has a strong protective effect to reduce breast cancer risk. Understanding the interplay of body mass index, menopause status, and measurement of non-dense breast area would help to clarify the contribution of non-dense breast area to breast cancer risk.
鲜有研究调查非致密区域或脂肪型乳房与乳腺密度和乳腺癌风险之间的关联。近期《乳腺癌研究》中的两篇文章探讨了在乳腺 X 光片中测量的绝对非致密乳腺面积的作用，结果却相互矛盾：一篇文章发现非致密乳腺面积与乳腺癌风险呈适度正相关，而另一篇文章则发现非致密乳腺面积具有较强的保护作用，可降低乳腺癌风险。了解体重指数、绝经状态和非致密乳腺面积测量之间的相互作用，将有助于阐明非致密乳腺面积对乳腺癌风险的贡献。
